CAJ | 학술논문

目的：了解铜绿假单胞菌（ PEA ）在院内的分布及耐药性变迁，为临床合理用药提供依据。方法：对我院2013—2014年住院患者送检做细菌培养的各类临床标本分离出的PEA及药敏结果进行回顾性分析。结果：2年共分离出74株PEA，其中以痰标本最多，占85.14％。 PEA主要来自神经内科、呼吸内科、神经外科及感染性疾病科，分别占35.14％、28.37％、13.52％、10.81％。 PEA 对常用抗生素的耐药率呈上升趋势。耐碳青霉烯类PEA菌株检出率也由2013年的12.50％上升至2014年的30.00％。结论：PEA的感染率和耐药率呈上升趋势，提示在临床工作中应注意手卫生及消毒隔离，保护易感患者，合理使用抗生素，做好多重耐药菌的预防与控制措施，减少耐药株的产生与传播。
목적：료해동록가단포균（ PEA ）재원내적분포급내약성변천，위림상합리용약제공의거。방법：대아원2013—2014년주원환자송검주세균배양적각류림상표본분리출적PEA급약민결과진행회고성분석。결과：2년공분리출74주PEA，기중이담표본최다，점85.14％。 PEA주요래자신경내과、호흡내과、신경외과급감염성질병과，분별점35.14％、28.37％、13.52％、10.81％。 PEA 대상용항생소적내약솔정상승추세。내탄청매희류PEA균주검출솔야유2013년적12.50％상승지2014년적30.00％。결론：PEA적감염솔화내약솔정상승추세，제시재림상공작중응주의수위생급소독격리，보호역감환자，합리사용항생소，주호다중내약균적예방여공제조시，감소내약주적산생여전파。
Objective:To understand the basic -level of pseudomonas aeruginosa(PEA) in hospital clinical distribution and drug resistance change , and to provide the basis for clinical rational drug use .Methods:In 2013—2014,hospitalized patients with bacteria culture of pseudomonas aeruginosa from the clinical specimens and their drug susceptibility results were retrospectively analyzed.Results:A total of 2 years,74 strains of pseudomonas aeruginosa was isolated , sputum specimens were the most for 85.14%.There were from neurology , respiratory medicine , neurosurgery and infectious diseases department , accounted for 35.14%,28.37%,13.52% and 35.14% respectively .PEA irologic resistance was obviously rising trend .For commonly used antibiotics ,PEA strain detection rate in resistance to carbon penicillium alkene were also on the increase from 12.50%in 2013 to 30.00%in 2014.Conclusion:The infection and resistance of PEA are rising , pay attention to hand hygiene and disinfection isolation, protect susceptible patients , rational use of antibiotics , make the prevention and control measures of multi -resistant bacteria better , reduce the formation and spread of drug -resistant strains .