中华消化外科杂志
中華消化外科雜誌
중화소화외과잡지
Chinese Journal of Digestive Surgery
2015年
11期
975-979
,共5页
急性胰腺炎%急性肺损伤%全身炎症反应综合征
急性胰腺炎%急性肺損傷%全身炎癥反應綜閤徵
급성이선염%급성폐손상%전신염증반응종합정
Acute pancreatitis%Acute lung injury%Systemic inflammatory response syndrome
作为急性胰腺炎早期炎症反应放大的结果,全身炎症反应综合征(SIRS)是导致胰腺炎肺损伤发生的主要原因,而早期合并的急性肺损伤或ARDS是导致急性胰腺炎患者高病死率的主要原因.一系列炎症介质及细胞因子在SIRS及胰腺炎肺损伤的发生发展过程中起着重要作用.因此,恢复炎症反应平衡状态成为目前治疗胰腺炎肺损伤的关键环节.
作為急性胰腺炎早期炎癥反應放大的結果,全身炎癥反應綜閤徵(SIRS)是導緻胰腺炎肺損傷髮生的主要原因,而早期閤併的急性肺損傷或ARDS是導緻急性胰腺炎患者高病死率的主要原因.一繫列炎癥介質及細胞因子在SIRS及胰腺炎肺損傷的髮生髮展過程中起著重要作用.因此,恢複炎癥反應平衡狀態成為目前治療胰腺炎肺損傷的關鍵環節.
작위급성이선염조기염증반응방대적결과,전신염증반응종합정(SIRS)시도치이선염폐손상발생적주요원인,이조기합병적급성폐손상혹ARDS시도치급성이선염환자고병사솔적주요원인.일계렬염증개질급세포인자재SIRS급이선염폐손상적발생발전과정중기착중요작용.인차,회복염증반응평형상태성위목전치료이선염폐손상적관건배절.
As a result of the early amplification of the inflammatory response in the acute pancreatitis, systemic inflammatory response syndrome (SIRS) is a main cause of acute pancreatitis-associated lung injury (APALI) , while early combined acute lung injury or acute respiratory distress syndrome causes a high mortality of acute pancreatitis.A series of inflammatory mediators and cytokines play important roles in the process of SIRS and APALI, therefore, inflammatory reaction restoring a balance becomes a key point of the treatment of pancreatitis lung injury.
