中国医学创新
中國醫學創新
중국의학창신
Medical Innovation of China
2015年
31期
49-52
,共4页
希罗达和唑来磷酸联合%乳腺癌多发骨转移%治疗效果%临床研究
希囉達和唑來燐痠聯閤%乳腺癌多髮骨轉移%治療效果%臨床研究
희라체화서래린산연합%유선암다발골전이%치료효과%림상연구
Xeloda combined with zoledronic acid%Breast cancer multiple bone metastasis%Treatment effect%Clinical study
目的：研究分析希罗达和唑来磷酸联合治疗乳腺癌多发骨转移的临床效果。方法：选取2011年12月1日-2014年12月1日经本院诊断并治疗的乳腺癌多发骨转移患者40例，采用随机数字表法将患者分为联合用药组和单一用药组，每组各20例。单一用药组给予希罗达，联合用药组在单一用药组的基础上给予静脉注射唑来磷酸治疗，分别记录两组患者治疗后的效果。结果：根据分析可得出联合用药组止痛有效率为85.00%，单一用药组止痛有效率为55.00%，联合用药组有效率明显高于单一用药组；且联合用药组骨转移灶治疗总有效率为65.00%明显高于单一用药组的35.00%，两组比较差异均有统计学意义（P<0.05）。结论：希罗达和唑来磷酸联合治疗乳腺癌多发骨转移效果好，安全性高，可以及时缓解疾病对患者造成的痛苦，值得在临床上推广普及。
目的：研究分析希囉達和唑來燐痠聯閤治療乳腺癌多髮骨轉移的臨床效果。方法：選取2011年12月1日-2014年12月1日經本院診斷併治療的乳腺癌多髮骨轉移患者40例，採用隨機數字錶法將患者分為聯閤用藥組和單一用藥組，每組各20例。單一用藥組給予希囉達，聯閤用藥組在單一用藥組的基礎上給予靜脈註射唑來燐痠治療，分彆記錄兩組患者治療後的效果。結果：根據分析可得齣聯閤用藥組止痛有效率為85.00%，單一用藥組止痛有效率為55.00%，聯閤用藥組有效率明顯高于單一用藥組；且聯閤用藥組骨轉移竈治療總有效率為65.00%明顯高于單一用藥組的35.00%，兩組比較差異均有統計學意義（P<0.05）。結論：希囉達和唑來燐痠聯閤治療乳腺癌多髮骨轉移效果好，安全性高，可以及時緩解疾病對患者造成的痛苦，值得在臨床上推廣普及。
목적：연구분석희라체화서래린산연합치료유선암다발골전이적림상효과。방법：선취2011년12월1일-2014년12월1일경본원진단병치료적유선암다발골전이환자40례，채용수궤수자표법장환자분위연합용약조화단일용약조，매조각20례。단일용약조급여희라체，연합용약조재단일용약조적기출상급여정맥주사서래린산치료，분별기록량조환자치료후적효과。결과：근거분석가득출연합용약조지통유효솔위85.00%，단일용약조지통유효솔위55.00%，연합용약조유효솔명현고우단일용약조；차연합용약조골전이조치료총유효솔위65.00%명현고우단일용약조적35.00%，량조비교차이균유통계학의의（P<0.05）。결론：희라체화서래린산연합치료유선암다발골전이효과호，안전성고，가이급시완해질병대환자조성적통고，치득재림상상추엄보급。
Objective:To study and analyze the clinical effect of Xeloda combined with zoledronic acid on treatment of multiple bone metastasis of breast cancer.Method: 40 breast cancer patients with multiple bone metastases in our hospital were selected from December 1, 2011 to December 1,2014 ,they were randomly divided into combined treatment group and single drug group by using random number table method, 20 cases in each group.Single drug group was given capecitabine, combination treatment group was given intravenous zoledronic acid on the base of control group, two groups curative effect were recorded.Result:The analgesic effective rate of combination treatment group was 85.00% obvious higher than single drug group of 55.00%; bone metastasis therapy effective rate of combination treatment group was 65.00% obvious than single drug group of 35.00%, the differences were statistically significant (P<0.05).Conclusion:The clinical effect of Xeloda combined with zoledronic acid has obvious effect on treatment of breast cancer multiple bone metastases,it is worthy of promotion.
