实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
2015年
10期
109-111
,共3页
胡川海%马丽%黄杨%李琳%曾逸笛%谭佳佳%胡志希
鬍川海%馬麗%黃楊%李琳%曾逸笛%譚佳佳%鬍誌希
호천해%마려%황양%리림%증일적%담가가%호지희
冠心病%中西医结合疗法%银丹心脑胶囊%半胱氨酸
冠心病%中西醫結閤療法%銀丹心腦膠囊%半胱氨痠
관심병%중서의결합요법%은단심뇌효낭%반광안산
Coronary disease%Integrated Chinese and Western medicine therapy%Yindan - xinnao capsule%Cysteine
目的：探讨银丹心脑胶囊联合西药治疗冠心病的临床疗效及其对血清同型半胱氨酸（Hcy）水平和血脂代谢的影响。方法选取2013年2月—2015年2月于湖南省中医研究院附属医院就诊的冠心病患者104例，按照随机数字表法分为对照组及观察组，每组52例。对照组患者采用西药治疗，观察组患者在此基础上联合银丹心脑胶囊口服治疗。8周为1个疗程，两组患者均治疗1个疗程。比较两组患者临床疗效，治疗前后血清 Hcy、血脂指标〔总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）〕。结果观察组患者临床疗效优于对照组（u =2.326，P =0.020）。两组患者治疗前血清 Hcy、TC、TG、HDL、LDL 水平比较，差异无统计学意义（P ﹥0.05）；治疗后观察组患者血清 Hcy、TC、TG、LDL 水平均低于对照组，血清 HDL 水平高于对照组（P ﹤0.05）。结论银丹心脑胶囊联合西药治疗冠心病的临床疗效确切，能有效降低血清 Hcy 水平及改善血脂代谢。
目的：探討銀丹心腦膠囊聯閤西藥治療冠心病的臨床療效及其對血清同型半胱氨痠（Hcy）水平和血脂代謝的影響。方法選取2013年2月—2015年2月于湖南省中醫研究院附屬醫院就診的冠心病患者104例，按照隨機數字錶法分為對照組及觀察組，每組52例。對照組患者採用西藥治療，觀察組患者在此基礎上聯閤銀丹心腦膠囊口服治療。8週為1箇療程，兩組患者均治療1箇療程。比較兩組患者臨床療效，治療前後血清 Hcy、血脂指標〔總膽固醇（TC）、三酰甘油（TG）、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）〕。結果觀察組患者臨床療效優于對照組（u =2.326，P =0.020）。兩組患者治療前血清 Hcy、TC、TG、HDL、LDL 水平比較，差異無統計學意義（P ﹥0.05）；治療後觀察組患者血清 Hcy、TC、TG、LDL 水平均低于對照組，血清 HDL 水平高于對照組（P ﹤0.05）。結論銀丹心腦膠囊聯閤西藥治療冠心病的臨床療效確切，能有效降低血清 Hcy 水平及改善血脂代謝。
목적：탐토은단심뇌효낭연합서약치료관심병적림상료효급기대혈청동형반광안산（Hcy）수평화혈지대사적영향。방법선취2013년2월—2015년2월우호남성중의연구원부속의원취진적관심병환자104례，안조수궤수자표법분위대조조급관찰조，매조52례。대조조환자채용서약치료，관찰조환자재차기출상연합은단심뇌효낭구복치료。8주위1개료정，량조환자균치료1개료정。비교량조환자림상료효，치료전후혈청 Hcy、혈지지표〔총담고순（TC）、삼선감유（TG）、고밀도지단백（HDL）、저밀도지단백（LDL）〕。결과관찰조환자림상료효우우대조조（u =2.326，P =0.020）。량조환자치료전혈청 Hcy、TC、TG、HDL、LDL 수평비교，차이무통계학의의（P ﹥0.05）；치료후관찰조환자혈청 Hcy、TC、TG、LDL 수평균저우대조조，혈청 HDL 수평고우대조조（P ﹤0.05）。결론은단심뇌효낭연합서약치료관심병적림상료효학절，능유효강저혈청 Hcy 수평급개선혈지대사。
Objective To explore the clinical effect of yindan - xinnao capsule combined with Western medicine on coronary heart disease and its impact on serum homocysteine level and blood lipid metabolism. Methods A total of 104 patients with coronary heart disease were selected in the Affiliated Hospital of Hu'nan Traditional Chinese Medicine Institute between February 2013 and February 2015,and they were divided into control group and observation group according to random number table,each of 52 cases. Patients of control group were given Western medicine,while patients of observation group were given extra yindan - xinnao capsule,both groups treated for 1 course(8 weeks as a course). Clinical effect,serum levels of homocysteine,TC,TG,HDL and LDL before and after treatment were compared between the two groups. Results The clinical effect of observation group was statistically significantly better than that of control group(u = 2. 326,P = 0. 020). No statistically significant differences of serum level of homocysteine,TC,TG,HDL or LDL was found between the two groups before treatment( P ﹥ 0. 05);after treatment,serum levels of homocysteine,TC,TG and LDL of observation group were statistically significantly lower than those of control group,while serum HDL level of observation group was statistically significantly higher than that of control group( P ﹤ 0. 05). Conclusion Yindan - xinnao capsule combined with Western medicine has certain clinical effect in treating coronary heart disease,can effectively reduce the serum homocysteine level and improve the blood lipid metabolism.
