CAJ | 학술논문

目的：：探讨米非司酮联合羊膜腔注射利凡诺对终止疤痕子宫妊娠的安全性及临床效果。方法：选取某院2011年2月~2013年2月收治的82例疤痕子宫中期妊娠孕妇作为研究对象,按随机数字表将患者分为对照组(n =41)和实验组(n =41)。实验组采用米非司酮(口服)及利凡诺(羊膜腔内注射)。对照组单纯应用羊膜腔内注射利凡诺。结果：实验组引产成功率为100.00%(41/41),对照组引产成功率为90.24%(37/41)；实验组引产成功率更高(χ2=4.205,P <0.05)。与对照组相比,实验组宫缩开始时间更早,胎盘娩出时间更短(t 分别为3.436,3.422；P <0.01)。实验组术后24h 出血量更少,产后出血发生率更低,宫颈裂伤发生率更低(P <0.05或 P <0.01)。此外,实验组Ⅰ级无痛例数更多(χ2=4.661,P <0.05)。结论：应用米非司酮联合羊膜腔注射利凡诺终止疤痕子宫妊娠具有引产成功率及完全流产率高,术后24h 出血量少,产后出血发生率低,并发症少,安全可靠等优点,应推广于临床。
목적：：탐토미비사동연합양막강주사리범낙대종지파흔자궁임신적안전성급림상효과。방법：선취모원2011년2월~2013년2월수치적82례파흔자궁중기임신잉부작위연구대상,안수궤수자표장환자분위대조조(n =41)화실험조(n =41)。실험조채용미비사동(구복)급리범낙(양막강내주사)。대조조단순응용양막강내주사리범낙。결과：실험조인산성공솔위100.00%(41/41),대조조인산성공솔위90.24%(37/41)；실험조인산성공솔경고(χ2=4.205,P <0.05)。여대조조상비,실험조궁축개시시간경조,태반면출시간경단(t 분별위3.436,3.422；P <0.01)。실험조술후24h 출혈량경소,산후출혈발생솔경저,궁경렬상발생솔경저(P <0.05혹 P <0.01)。차외,실험조Ⅰ급무통례수경다(χ2=4.661,P <0.05)。결론：응용미비사동연합양막강주사리범낙종지파흔자궁임신구유인산성공솔급완전유산솔고,술후24h 출혈량소,산후출혈발생솔저,병발증소,안전가고등우점,응추엄우림상。
Objective:To investigate the clinical effect of intra-amniotic infection of Rivanol plus Mifepris-tone on terminating CSP and its safety.Methods:Select 82 patients with SCP within the second trimester in some hospital during the period from February 201 1 to February 2013 as the research object,divide them into control group(n = 41 )and experiment group (n = 41 )according to random number table.The experiment group orally administrated Mifepristone and were injected with Rivanol into amniotic cavity.While in control group ,they were merely treated with intra-amniotic infection of Rivanol.Results:The success rate of induc-tion in experiment group was 100.00%(41/41),while in control group,the rate was only 90.24%(37/41 ), namely,the success rate of induction in experiment group was higher (χ2 =4.205,P <0.05 );to compare with control group,the occurrence of UC in experiment group was earlier,the delivery time of placenta was shorter,the delivery time of placenta in the 2 group were 3.436 and 3.422,P <0.01;in experiment group, blood loss in the following 24 hours after operation was relatively less and the occurrence of postpartum hem-orrhage was lower,the occurrence of cervical laceration was also lower(P <0.05or P <0.01 );besides,more cases had I-level painless delivery (χ2 =4.661,P <0.05.Conclusion:The success induction rate and complete abortion rate was high ,and the blood loss was less in the following 24 hours after operation and there would be less complication if applying intra-amniotic infection of Rivanol plus Mifepristone to terminate CSP,it is safe and reliable,it is worthy of clinical popularization.