数理医药学杂志
數理醫藥學雜誌
수리의약학잡지
Journal of Mathematical Medicine
2015年
12期
1778-1779,1780
,共3页
沈学艺%陈宇峰%陈德烽%许笃行%陈谭根
瀋學藝%陳宇峰%陳德烽%許篤行%陳譚根
침학예%진우봉%진덕봉%허독행%진담근
解剖性肝切除术%非解剖性肝切除术%晚期肝癌%安全性%临床疗效
解剖性肝切除術%非解剖性肝切除術%晚期肝癌%安全性%臨床療效
해부성간절제술%비해부성간절제술%만기간암%안전성%림상료효
anatomical hepatectomy%non-anatomical hepatectomy%advanced liver cancer%security%clinical curative effect
目的::对比分析晚期肝癌患者中行解剖性肝切除术与非解剖性肝切除术安全性与临床疗效的优劣。方法:回顾性分析98例行肝切除术的晚期肝癌患者临床资料,59例行解剖性肝切除术的患者归入研究组、39例行非解剖性肝切除术的患者归入对照组,对比两组患者术中、术后效果。结果:(1)术中效果显示,观察组手术时间平均为(271.5±97.4)min,切缘有效率为89.8%,优于对照组(188.5±70.7)min 和53.8%,差异有统计学意义(P <0.05);但两组术中出血量、术中输血量无统计学意义(P >0.05);(2)观察组预后效果要优于对照组,术后3d 血清 ALT 均值为(270.5±94.1)U/L,对照组则高达(501.6±115.6)U/L,术后1年复发率、生存率也优于对照组,上述各项差异均有统计学意义(P <0.05)。结论:解剖性肝切除术具有更高的安全性与临床疗效,对于须行肝切除的晚期肝癌患者,更值得采用。
目的::對比分析晚期肝癌患者中行解剖性肝切除術與非解剖性肝切除術安全性與臨床療效的優劣。方法:迴顧性分析98例行肝切除術的晚期肝癌患者臨床資料,59例行解剖性肝切除術的患者歸入研究組、39例行非解剖性肝切除術的患者歸入對照組,對比兩組患者術中、術後效果。結果:(1)術中效果顯示,觀察組手術時間平均為(271.5±97.4)min,切緣有效率為89.8%,優于對照組(188.5±70.7)min 和53.8%,差異有統計學意義(P <0.05);但兩組術中齣血量、術中輸血量無統計學意義(P >0.05);(2)觀察組預後效果要優于對照組,術後3d 血清 ALT 均值為(270.5±94.1)U/L,對照組則高達(501.6±115.6)U/L,術後1年複髮率、生存率也優于對照組,上述各項差異均有統計學意義(P <0.05)。結論:解剖性肝切除術具有更高的安全性與臨床療效,對于鬚行肝切除的晚期肝癌患者,更值得採用。
목적::대비분석만기간암환자중행해부성간절제술여비해부성간절제술안전성여림상료효적우렬。방법:회고성분석98례행간절제술적만기간암환자림상자료,59례행해부성간절제술적환자귀입연구조、39례행비해부성간절제술적환자귀입대조조,대비량조환자술중、술후효과。결과:(1)술중효과현시,관찰조수술시간평균위(271.5±97.4)min,절연유효솔위89.8%,우우대조조(188.5±70.7)min 화53.8%,차이유통계학의의(P <0.05);단량조술중출혈량、술중수혈량무통계학의의(P >0.05);(2)관찰조예후효과요우우대조조,술후3d 혈청 ALT 균치위(270.5±94.1)U/L,대조조칙고체(501.6±115.6)U/L,술후1년복발솔、생존솔야우우대조조,상술각항차이균유통계학의의(P <0.05)。결론:해부성간절제술구유경고적안전성여림상료효,대우수행간절제적만기간암환자,경치득채용。
Objective:To compare and analyze the safety and the effect of anatomical hepatectomy and non-anatomical hepatectomy on patients with advanced liver cancer.Methods:Retrospectively analyze the clinical data of 98 patients with advanced liver cancer who had received hepatectomy.59 patients underwent anatomi-cal hepatectomy were defined as research group,39 patients underwent non-anatomical hepatectomy were supposed as the control group,compared intraoperative and postoperative effect in the 2 groups.Results:(1) intraoperative effect showed that,in observation group ,the average operating time was (271.5±97.4)min, the effective rate of cut edge was 89.8%,which is (188.5±70.7)min and 53.8% shorter than of the control group ,the differences was statistically significant (P <0.05);while the difference between the two groups in intraoperative blood loss,intraoperative blood transfusion were not statistically significant P >0.05).(2) in observation group ,the prognostic effect is significantly superior to that in control group,the ALT con-tained in serum within the 3 days after operation was (270.5±94.1)U/L ,while in control group ,it ws up to (501.6 ± 1 15.6)U/L,postoperative recurrence rate,survival rate within 1 year was obviously better than that of control group,the differences above are all significant,and are statistically significant(P < 0.05 ). Conclusion:Natomical hepatectomy is with higher safety and is clinically more effective ,it is worthy of adop-tion for patients with advanced liver cancer needing hepatectomy.