数理医药学杂志
數理醫藥學雜誌
수리의약학잡지
Journal of Mathematical Medicine
2015年
12期
1747-1748,1749
,共3页
重度有机磷中毒%多器官功能障碍
重度有機燐中毒%多器官功能障礙
중도유궤린중독%다기관공능장애
severe organophosphorus poisoning%multiple organ dysfunction syndrome
目的：：探讨重度有机磷中毒致多器官功能障碍的病理以及诊治手段。方法：将某院收治的52例 MODS 患者作为观察对象,OBG 组患者给予大黄酚治疗,COG 组患者给予甘露醇治疗,统计病理数据,评价不同治疗方法治疗的有效性。结果：OBG 组治疗后血清胆碱酯酶值为(0.5±0.20)kU/L,中间综合症有1例,占比3.85%,死亡2例,占比7.69%,住院天数为(10.21±3.5)d,症状消失有24例,占比92.31%；COG 组患者治疗后血清胆碱酯酶值为(0.4±0.09)kU/L,中间综合症有3例,占比11.54%,死亡5例,占比19.23%,住院天数为(17.82±5.3)d,症状消失有21例,占比80.77%,组间比较具有显著差异和统计学意义,P <0.05。结论：早期的呼吸道、胃肠道清理是治疗的基础,并密切关注对患者的器官功能状态的预先监测,保护胃肠道黏膜,根据临床症状的特点积极治疗,从而降低器官累及数目,不断提高患者的救治成功率。
目的：：探討重度有機燐中毒緻多器官功能障礙的病理以及診治手段。方法：將某院收治的52例 MODS 患者作為觀察對象,OBG 組患者給予大黃酚治療,COG 組患者給予甘露醇治療,統計病理數據,評價不同治療方法治療的有效性。結果：OBG 組治療後血清膽堿酯酶值為(0.5±0.20)kU/L,中間綜閤癥有1例,佔比3.85%,死亡2例,佔比7.69%,住院天數為(10.21±3.5)d,癥狀消失有24例,佔比92.31%；COG 組患者治療後血清膽堿酯酶值為(0.4±0.09)kU/L,中間綜閤癥有3例,佔比11.54%,死亡5例,佔比19.23%,住院天數為(17.82±5.3)d,癥狀消失有21例,佔比80.77%,組間比較具有顯著差異和統計學意義,P <0.05。結論：早期的呼吸道、胃腸道清理是治療的基礎,併密切關註對患者的器官功能狀態的預先鑑測,保護胃腸道黏膜,根據臨床癥狀的特點積極治療,從而降低器官纍及數目,不斷提高患者的救治成功率。
목적：：탐토중도유궤린중독치다기관공능장애적병리이급진치수단。방법：장모원수치적52례 MODS 환자작위관찰대상,OBG 조환자급여대황분치료,COG 조환자급여감로순치료,통계병리수거,평개불동치료방법치료적유효성。결과：OBG 조치료후혈청담감지매치위(0.5±0.20)kU/L,중간종합증유1례,점비3.85%,사망2례,점비7.69%,주원천수위(10.21±3.5)d,증상소실유24례,점비92.31%；COG 조환자치료후혈청담감지매치위(0.4±0.09)kU/L,중간종합증유3례,점비11.54%,사망5례,점비19.23%,주원천수위(17.82±5.3)d,증상소실유21례,점비80.77%,조간비교구유현저차이화통계학의의,P <0.05。결론：조기적호흡도、위장도청리시치료적기출,병밀절관주대환자적기관공능상태적예선감측,보호위장도점막,근거림상증상적특점적겁치료,종이강저기관루급수목,불단제고환자적구치성공솔。
Objective:To investigate the pathology of multiple organ dysfunction syndrome caused by se-vere organophosphorus poisoning and treatment methods.Methods:A total of 52 patients with MODS were taken into this research.And they were divided into OBG (25 patients)and COG(25 patients)Group according to random number table.the OBG were treated with chrysophanol and the COG were treated with mannitol. Patients'pathological data of the two groups were collected and,the effectiveness of each method was ana lyzed.Results:In OBG ,the value of cholinesterase contained in serum was (0.5 ±0.20)kU/L,1 case was with intermediate syndrome,which accounted for 3.85% of all,2 cases died,which accounted for 7.698% of all,the length of stays was (10.21±3.5),symptom disappearing case was 24 and took up 92.31% of all;In the COG Group,the value of cholinesterase in serum was(0.4 ±0.09 )kU/L,3 patients were with intermediate syndrome,which took up 1 1.54%,5 patients died,which accounted for 1 9.23%,the length of stays was (17.82±5.3),symptoms of 21 cases disappeared,wich took up 80.77%,the differences between the 2 groups were obvious and statistically significant P <0.05.Conclusion:Respiratory tract,gastrointestinal tract clean-ing in early stage is the basis of treatment,and pay close attention to the functional status of patients'organs and make pre-monitoring so as to protect mucosa of gastrointestinal tract ,and positively give out treatment according to the characteristics of clinical symptoms ,so as to reduce the number of organs involved,and continuously improve the success rate of treatment.
