中国医学创新
中國醫學創新
중국의학창신
Medical Innovation of China
2015年
30期
99-101
,共3页
宫颈癌筛查%人乳头瘤病毒%新柏氏液基细胞学
宮頸癌篩查%人乳頭瘤病毒%新柏氏液基細胞學
궁경암사사%인유두류병독%신백씨액기세포학
Cervical cancer screening%Human papilloma virus%Thinprep cytologic test
目的:分析长沙市部分女性公务员宫颈高危型HPV感染与TCT相关性.方法:对2012年10-12月在长沙市妇幼保健院健康管理中心体检的10 117例女性公务员按照年龄进行分组,并采用PCR加膜杂交法进行HPV分型检测及TCT检测.结果:高危型HPV感染率为8.98%(909/10 117),检出比例占前3位的高危型HPV分别是HPV52型(31.46%)、58型(19.36%)及16型(16.17%),其中单一、双重及三重感染所占比例分别为83.06%、13.42%、3.52%;909例高危型HPV感染者中细胞学异常者76例(8.4%),其中高危型HPV16、33型出现细胞学HSIL病变的比例远高于其他分型.结论:HPV分型与TCT联合检测可以提高宫颈癌筛查有效性,对HPV16、33型感染的女性应重视宫颈癌筛查.
目的:分析長沙市部分女性公務員宮頸高危型HPV感染與TCT相關性.方法:對2012年10-12月在長沙市婦幼保健院健康管理中心體檢的10 117例女性公務員按照年齡進行分組,併採用PCR加膜雜交法進行HPV分型檢測及TCT檢測.結果:高危型HPV感染率為8.98%(909/10 117),檢齣比例佔前3位的高危型HPV分彆是HPV52型(31.46%)、58型(19.36%)及16型(16.17%),其中單一、雙重及三重感染所佔比例分彆為83.06%、13.42%、3.52%;909例高危型HPV感染者中細胞學異常者76例(8.4%),其中高危型HPV16、33型齣現細胞學HSIL病變的比例遠高于其他分型.結論:HPV分型與TCT聯閤檢測可以提高宮頸癌篩查有效性,對HPV16、33型感染的女性應重視宮頸癌篩查.
목적:분석장사시부분녀성공무원궁경고위형HPV감염여TCT상관성.방법:대2012년10-12월재장사시부유보건원건강관리중심체검적10 117례녀성공무원안조년령진행분조,병채용PCR가막잡교법진행HPV분형검측급TCT검측.결과:고위형HPV감염솔위8.98%(909/10 117),검출비례점전3위적고위형HPV분별시HPV52형(31.46%)、58형(19.36%)급16형(16.17%),기중단일、쌍중급삼중감염소점비례분별위83.06%、13.42%、3.52%;909례고위형HPV감염자중세포학이상자76례(8.4%),기중고위형HPV16、33형출현세포학HSIL병변적비례원고우기타분형.결론:HPV분형여TCT연합검측가이제고궁경암사사유효성,대HPV16、33형감염적녀성응중시궁경암사사.
Objective:To analyze the correlation of cervical high risk human papilloma virus infection and thinprep cytologic test in part of female civil servants in Changsha.Method:10 117 female civil servants who were examined in the health management center of Changsha maternal and child health hospital from October 2012 to December 2012 were grouped according to their ages.HPV genotyping was tested by PCR and membrane hybridization.The examination of TCT was also given to the patients.Result:The infection rate of high risk HPV was 8.98%(909/10 117). Among all the high-risk HPV,the top 3 were HPV52(31.46%),HPV58(19.36%) and HPV16(16.17%).The rates of single infection,double infections and three infections were 83.06%,13.42% and 3.52% respectively.In the 909 cases of high-risk HPV infection,the number of cytological abnormalities was 76(8.4%).The HSIL in high-risk type HPV16 and HPV33 were higher than other types.Conclusion:The joint of HPV genotyping and TCT can improve the effectiveness of cervical cancer screening.Cervical cancer screening shall be paid attention in female who has been infected HPV16 and HPV33.
