CAJ | 학술논문

肥胖是指体内脂肪堆积过多和(或)分布异常的一种慢性代谢性疾病.肥胖的病因未明,目前认为与遗传因素、环境因素等多种因素相互作用有关.高脂饮食是与肥胖存在紧密联系的环境因素之一,但相关作用机制仍不明确,可能与长期高脂饮食所致的消化道脂质感应信号通路受损、胃肠道激素分泌紊乱、肠道菌群的改变有关.
비반시지체내지방퇴적과다화(혹)분포이상적일충만성대사성질병.비반적병인미명,목전인위여유전인소、배경인소등다충인소상호작용유관.고지음식시여비반존재긴밀련계적배경인소지일,단상관작용궤제잉불명학,가능여장기고지음식소치적소화도지질감응신호통로수손、위장도격소분비문란、장도균군적개변유관.
Obesity is a chronic metabolic disease,which refers to the abnormal fat distribution and (or) excessive fat accumulation.The cause of obesity is unknown, but is associated with various factors including genetic factors and environmental factors.There is a strong direct association between high-fat diet and obesity.However, the mechanisms of chronic higth-fat consumption in the development of obesity are still poorly understood.Accumulating evidence shows that the mechanisms may be related to gastrointestinal lipid detection,abnormal secretion of gut peptides, and change of intestinal microbiota.