CAJ | 학술논문

目的：探究游离PSA（ fPSA）和总PSA（ tPSA）的比值（ fPSA／tPSA）及前列腺抗原密度（ PSAD）在前列腺疾病诊断中的价值。方法收集前列腺炎、良性前列腺增生、经病理明确诊断的前列腺恶性肿瘤患者共458例的tPSA并计算各例fPSA／tPSA，PSAD值。结果458例患者中52例Ⅰ，Ⅱ型前列腺炎组为6．01±3．25，0．31±0．22，0．24±0．33；75例Ⅲ，Ⅳ型前列腺炎组为4．16±1．03，0．24±0．15，0．20±0．17；234例良性前列腺增生组为17．25±3．87，0．31±0．27，0．35±0．12；97例前列腺癌组为51．35±49．23，0．13±0．11，0．69±0．12。结论 fPSA／tPSA及PSAD的联合分析在前列腺疾病的诊断中明显优于单纯使用PSA。
목적：탐구유리PSA（ fPSA）화총PSA（ tPSA）적비치（ fPSA／tPSA）급전렬선항원밀도（ PSAD）재전렬선질병진단중적개치。방법수집전렬선염、량성전렬선증생、경병리명학진단적전렬선악성종류환자공458례적tPSA병계산각례fPSA／tPSA，PSAD치。결과458례환자중52례Ⅰ，Ⅱ형전렬선염조위6．01±3．25，0．31±0．22，0．24±0．33；75례Ⅲ，Ⅳ형전렬선염조위4．16±1．03，0．24±0．15，0．20±0．17；234례량성전렬선증생조위17．25±3．87，0．31±0．27，0．35±0．12；97례전렬선암조위51．35±49．23，0．13±0．11，0．69±0．12。결론 fPSA／tPSA급PSAD적연합분석재전렬선질병적진단중명현우우단순사용PSA。
[ ABSTRACT] Objective To explore fPSA/tPSA and PSAD's value in the diagnosis of prostatic diseases.Meth-ods 458 patients with prostatic diseases were collected,including prostatitis,benign prostatic hyperplasia and the patho-logical diagnosis of prostate malignant tumor,and then calculated example fPSA/tPSA,PSAD values.Results Fifty-two cases of typeⅠⅡprostatitis were 6.01 ±3.25,0.31 ±0.22,0.24 ±0.33;75 cases of tpyeⅢ,Ⅳprostatitis group were 4.16 ±1.03,0.24 ±0.15,0.20 ±0.17;234 cases of benign prostatic hyperplasia group were 17.25 ±3.87,0.31 ±0. 27,0.35 ±0.12;97 cases of prostate cancer group were 51.35 ±49.23,0.13 ±0.11,0.69 ±0.12.Conclusion The conjoint analysis of fPSA/tPSA and PSAD in the diagnosis of prostate disease is superior to pure use of PSA.