CAJ | 학술논문

目的：探讨血清唾液酸在毛细支气管炎患儿中混合感染的应用价值。方法选取2014年6月～2015年7月在潍坊市人民医院住院治疗的100例毛细支气管炎患儿，利用Olympus-2700全自动生化分析仪检测血清唾液酸含量；同时利用间接免疫荧光法检测患儿血清中9项呼吸道病原体。结果血清唾液酸含量占前3位的感染患儿分别为混合感染者（1000．5±49．9）mg／L、其次为肺炎支原体感染者（920．4±97．0）mg／L和副流感病毒感染者（844．7±25．0）mg／L，其中混合感染患儿高于其他患儿，差异有统计学意义（P＜0．05）；100例患儿中有22例为混合感染（22．0％），混合感染患儿中又以混合肺炎支原体多见（86．4％）。结论血清唾液酸水平越高，提示混合感染的可能性越大；肺炎支原体容易混合其它病原体感染。
목적：탐토혈청타액산재모세지기관염환인중혼합감염적응용개치。방법선취2014년6월～2015년7월재유방시인민의원주원치료적100례모세지기관염환인，이용Olympus-2700전자동생화분석의검측혈청타액산함량；동시이용간접면역형광법검측환인혈청중9항호흡도병원체。결과혈청타액산함량점전3위적감염환인분별위혼합감염자（1000．5±49．9）mg／L、기차위폐염지원체감염자（920．4±97．0）mg／L화부류감병독감염자（844．7±25．0）mg／L，기중혼합감염환인고우기타환인，차이유통계학의의（P＜0．05）；100례환인중유22례위혼합감염（22．0％），혼합감염환인중우이혼합폐염지원체다견（86．4％）。결론혈청타액산수평월고，제시혼합감염적가능성월대；폐염지원체용역혼합기타병원체감염。
[ ABSTRACT] Objective To explore application value of serum sialic acid in mixed infection of bronchiolitis. Methods Serum sialic acid was measured by Olympus-2700 Automatic biochemical analyzer.The IgM antibodies against nine types of respiratory pathogens were detected by Indirect immunofluorescence assay in 100 bronchiolitis infants trea-ted in weifang people's hospital from June 2014 to July 2015.Results The serum sialic acid in infants infected mixed pathogens was the most highest[(1000.5 ±49.9)mg/L],followed by Mycoplasma pneumoniae[(920.4 ±97.0)mg/L] and parainfluenza virus[(844.7 ±25.0)mg/L],the first group was higher than other groups,there were statistical sig-nificance in them(P<0.05);22 infants had mixed pathogens in 100 infants(22.0%).Mycoplasma pneumoniae was the most common in 22 infants of mixed infection(86.4%) .Conclusion The higher the serum sialic acid,the more possi-ble the mixed infection;Mycoplasma pneumoniae easily appear in mixed infection.