实用癌症杂志
實用癌癥雜誌
실용암증잡지
The Practical Journal of Cancer
2015年
12期
1877-1880
,共4页
郭剑%周淑卿%李杰%陈渊%郑少鹏
郭劍%週淑卿%李傑%陳淵%鄭少鵬
곽검%주숙경%리걸%진연%정소붕
大肠癌%开放式手术%腹腔镜%大肠癌根治术%营养状况
大腸癌%開放式手術%腹腔鏡%大腸癌根治術%營養狀況
대장암%개방식수술%복강경%대장암근치술%영양상황
Colorectal cancer%Open surgery%Laparoscopic%Colorectal cancer resection%Nutritional status
目的:比较开放式手术与腹腔镜下大肠癌根治术治疗大肠癌患者围手术期营养状况,从而选择最佳治疗方案以改善其预后。方法90例大肠癌患者按照随机数字表法分组为对照组与观察组,分别为45例。对照组采用传统开放式手术治疗;观察组采用腹腔镜辅助大肠癌根治术治疗。比较2组患者围手术期情况和术后恢复及并发症、手术前后营养状况及生活质量,随访1年,统计2组患者生存及复发例数。结果观察组平均手术时间、术中平均出血量、术后排气时间及平均住院时间分别为(141.2±26.5) min、(26.4±5.8) ml、(26.1±8.7) h、(9.8±3.9)天,明显少于对照组[(171.5±29.7) min、(148.6±16.5) ml、(37.8±7.6) h、(14.9±6.4)天],具有统计学意义,P<0.05;观察组腹腔并发症和切口并发症者分别为3例、1例,并发症发生率分别为6.7%、2.2%,明显低于对照组[12例、7例,26.7%、15.6%],具有统计学意义,P<0.05。观察组术后各项血清指标与术前比较,P>0.05;对照组术后各项血清指标与术前比较,P<0.05;观察组术后各项血清指标均明显高于对照组,具有统计学意义,P<0.05。2组治疗后各项生活质量均较术前明显改善,且观察组各项生活质量改善优于对照组,具有统计学意义,P<0.05。结论与传统开放式手术治疗相比,应用腹腔镜辅助大肠癌根治术治疗大肠癌患者,可减少术后并发症,改善其营养状况,从而促进其康复,提高其生活质量。
目的:比較開放式手術與腹腔鏡下大腸癌根治術治療大腸癌患者圍手術期營養狀況,從而選擇最佳治療方案以改善其預後。方法90例大腸癌患者按照隨機數字錶法分組為對照組與觀察組,分彆為45例。對照組採用傳統開放式手術治療;觀察組採用腹腔鏡輔助大腸癌根治術治療。比較2組患者圍手術期情況和術後恢複及併髮癥、手術前後營養狀況及生活質量,隨訪1年,統計2組患者生存及複髮例數。結果觀察組平均手術時間、術中平均齣血量、術後排氣時間及平均住院時間分彆為(141.2±26.5) min、(26.4±5.8) ml、(26.1±8.7) h、(9.8±3.9)天,明顯少于對照組[(171.5±29.7) min、(148.6±16.5) ml、(37.8±7.6) h、(14.9±6.4)天],具有統計學意義,P<0.05;觀察組腹腔併髮癥和切口併髮癥者分彆為3例、1例,併髮癥髮生率分彆為6.7%、2.2%,明顯低于對照組[12例、7例,26.7%、15.6%],具有統計學意義,P<0.05。觀察組術後各項血清指標與術前比較,P>0.05;對照組術後各項血清指標與術前比較,P<0.05;觀察組術後各項血清指標均明顯高于對照組,具有統計學意義,P<0.05。2組治療後各項生活質量均較術前明顯改善,且觀察組各項生活質量改善優于對照組,具有統計學意義,P<0.05。結論與傳統開放式手術治療相比,應用腹腔鏡輔助大腸癌根治術治療大腸癌患者,可減少術後併髮癥,改善其營養狀況,從而促進其康複,提高其生活質量。
목적:비교개방식수술여복강경하대장암근치술치료대장암환자위수술기영양상황,종이선택최가치료방안이개선기예후。방법90례대장암환자안조수궤수자표법분조위대조조여관찰조,분별위45례。대조조채용전통개방식수술치료;관찰조채용복강경보조대장암근치술치료。비교2조환자위수술기정황화술후회복급병발증、수술전후영양상황급생활질량,수방1년,통계2조환자생존급복발례수。결과관찰조평균수술시간、술중평균출혈량、술후배기시간급평균주원시간분별위(141.2±26.5) min、(26.4±5.8) ml、(26.1±8.7) h、(9.8±3.9)천,명현소우대조조[(171.5±29.7) min、(148.6±16.5) ml、(37.8±7.6) h、(14.9±6.4)천],구유통계학의의,P<0.05;관찰조복강병발증화절구병발증자분별위3례、1례,병발증발생솔분별위6.7%、2.2%,명현저우대조조[12례、7례,26.7%、15.6%],구유통계학의의,P<0.05。관찰조술후각항혈청지표여술전비교,P>0.05;대조조술후각항혈청지표여술전비교,P<0.05;관찰조술후각항혈청지표균명현고우대조조,구유통계학의의,P<0.05。2조치료후각항생활질량균교술전명현개선,차관찰조각항생활질량개선우우대조조,구유통계학의의,P<0.05。결론여전통개방식수술치료상비,응용복강경보조대장암근치술치료대장암환자,가감소술후병발증,개선기영양상황,종이촉진기강복,제고기생활질량。
Objective To compare the perioperative nutritional status of colorectal cancer patients treated with open sur-gery and laparoscopic colorectal resection,and select the best treatment option to improve the prognosis.Methods 90 cases of colorectal cancer patients,according to the random number table,were grouped into the control group and the observation group, 45 cases in each.The control group received traditional open surgery;and the observation group received laparoscopic surgery. Perioperative status,postoperative recovery and complications,and nutritional status and life quality before and after surgery of the 2 groups were compared,follow-up was 1 year,and the number of survival and recurrence were recorded.Results The mean op-erative time,the average blood loss,postoperative discharge time and the average length of stay in the observation group were re-spectively (141.2 ±26.5) min,(26.4 ±5.8) ml,(26.1 ±8.7) h,(9.8 ±3.9) days,which were significantly shorter than those of the control group (171.5 ±29.7) min,(148.6 ±16.5) ml,(37.8 ±7.6) h,(14.9 ±6.4) days,there had statistically significant difference,P<0.05;in the observation group,patients had 3 cases with complications and 1 case incision concurrency, complication rates were 6.7%,2.2%,which were significantly lower than those of the control group,12 cases,7 cases,26.7%, 15.6%,there had statistically significant difference,P<0.05.Postoperative serum markers in the observation group were com-pared with before the surgery,P>0.05;in the control group,the serum markers after surgery were compared with before the sur-gery,P<0.05;the postoperative serum markers in the observation group were significantly higher than that of the control group, with statistically significant,P <0.05.After treatment,the quality of life compared with before surgery were significantly im-proved,the quality of life in the observation group was better than that of the control group,there had statistically significant differ-ence,P<0.05.Conclusion Compared with traditional open surgery,laparoscopic-assisted resection of colorectal cancer can re-duce the incidence of postoperative complications and improve nutritional status,so as to promote rehabilitation and improve quali-ty of life.