中国肝脏病杂志（电子版）
中國肝髒病雜誌（電子版）
중국간장병잡지（전자판）
Chinese Journal of Liver Diseases (Electronic Version)
2015年
3期
112-115
,共4页
非酒精性脂肪性肝病%代谢综合征%动脉粥样硬化%脉搏波传导速度%心血管疾病
非酒精性脂肪性肝病%代謝綜閤徵%動脈粥樣硬化%脈搏波傳導速度%心血管疾病
비주정성지방성간병%대사종합정%동맥죽양경화%맥박파전도속도%심혈관질병
Non-alcoholic fatty liver disease%Metabolic syndrome%Atherosclerosis%Pulse wave velocity%Cardiovascular diseas
目的：探讨非酒精性脂肪性肝病（NAFLD）与脉搏波传导速度（PWV）的关系。方法对纳入研究的208例体检者相关临床指标进行回顾性分析。结果 NAFLD的总患病率为16.8%（35/208），男女之间NAFLD患病率无明显统计学差异；NAFLD组的年龄、体重、腰围、BMI、收缩压、血糖、甘油三脂、LDL、ALT、GGT、平均BaPWV均高于非NAFLD组；男性和女性NAFLD组平均BaPWV均高于各自的非NAFLD组；多元逐步回归分析显示，以平均BaPWV为因变量，变量年龄、BMI、收缩压、血糖、LDL、GGT及NAFLD进入回归方程；而在NAFLD组内，变量BMI、收缩压、血糖、LDL、GGT进入回归方程；NAFLD组内变量BMI、收缩压、血糖、LDL均与平均BaPWV呈现明显的正相关性。结论 NAFLD患者的动脉硬化程度高于对照组，将PWV作为评估NAFLD患者动脉硬化程度的指标具有一定的实用价值。
目的：探討非酒精性脂肪性肝病（NAFLD）與脈搏波傳導速度（PWV）的關繫。方法對納入研究的208例體檢者相關臨床指標進行迴顧性分析。結果 NAFLD的總患病率為16.8%（35/208），男女之間NAFLD患病率無明顯統計學差異；NAFLD組的年齡、體重、腰圍、BMI、收縮壓、血糖、甘油三脂、LDL、ALT、GGT、平均BaPWV均高于非NAFLD組；男性和女性NAFLD組平均BaPWV均高于各自的非NAFLD組；多元逐步迴歸分析顯示，以平均BaPWV為因變量，變量年齡、BMI、收縮壓、血糖、LDL、GGT及NAFLD進入迴歸方程；而在NAFLD組內，變量BMI、收縮壓、血糖、LDL、GGT進入迴歸方程；NAFLD組內變量BMI、收縮壓、血糖、LDL均與平均BaPWV呈現明顯的正相關性。結論 NAFLD患者的動脈硬化程度高于對照組，將PWV作為評估NAFLD患者動脈硬化程度的指標具有一定的實用價值。
목적：탐토비주정성지방성간병（NAFLD）여맥박파전도속도（PWV）적관계。방법대납입연구적208례체검자상관림상지표진행회고성분석。결과 NAFLD적총환병솔위16.8%（35/208），남녀지간NAFLD환병솔무명현통계학차이；NAFLD조적년령、체중、요위、BMI、수축압、혈당、감유삼지、LDL、ALT、GGT、평균BaPWV균고우비NAFLD조；남성화녀성NAFLD조평균BaPWV균고우각자적비NAFLD조；다원축보회귀분석현시，이평균BaPWV위인변량，변량년령、BMI、수축압、혈당、LDL、GGT급NAFLD진입회귀방정；이재NAFLD조내，변량BMI、수축압、혈당、LDL、GGT진입회귀방정；NAFLD조내변량BMI、수축압、혈당、LDL균여평균BaPWV정현명현적정상관성。결론 NAFLD환자적동맥경화정도고우대조조，장PWV작위평고NAFLD환자동맥경화정도적지표구유일정적실용개치。
Objective To investigate the relationship between non-alcoholic fatty liver disease and pulse wave velocity. Methods The clinical data of 208 subjects enrolled were analyzed retrospectively. Results The prevalence of NAFLD was 16.8% (35/208), and there was no significant difference in the prevalence of NAFLD between male and female. Compared with normal group, NAFLD subjects were older and had significant higher body weight, waist circumference, BMI, systolic blood pressure, blood glucose, triglycerides, LDL, ALT and GGT. Compared to controls, the average BaPWV of NAFLD subjects both male and female were significant higer. In multiple regression analysis, age, BMI, systolic blood pressure, blood glucose, LDL, GGT and NAFLD contributed to average BaPWV. Furthermore, in the NAFLD subjects, BMI, systolic blood pressure, blood glucose and LDL contributed to average BaPWV. There was positive correlation between BMI, systolic blood pressure, blood glucose, LDL and average BaPWV in NAFLD group. Conclusions Compared to controls, NAFLD subjects had more severe atherosclerosis, and PWV was a valuable indicator to assess the extent of atherosclerosis in NAFLD subjects.
