实用临床医学
實用臨床醫學
실용림상의학
Practical Clinical Medicine
2015年
10期
93-96
,共4页
毕声荣(综述)%余方圆(审校)
畢聲榮(綜述)%餘方圓(審校)
필성영(종술)%여방원(심교)
骨髓间充质干细胞%股骨头坏死,早期%干细胞移植
骨髓間充質榦細胞%股骨頭壞死,早期%榦細胞移植
골수간충질간세포%고골두배사,조기%간세포이식
bone marrow mesenchymal stem cells%osteonecrosis of femeral head%stem cell transplantation
骨髓间充质干细胞（bone marrow mesenchymal stem cells，BMSCs）在特定环境下能向骨、血管等组织细胞诱导分化，促进股骨头坏死（osteonecrosis of the femeral head，ONFH）局部新生血管的形成及坏死区骨组织的修复替代，并具有易于获得、增殖速度快、免疫原性低等优点，可作为组织工程优质种子细胞，在早期股骨头坏死修复方面具有广阔的临床应用前景。本文就 BMSCs 治疗早期 ONFH 的研究进展作一综述。
骨髓間充質榦細胞（bone marrow mesenchymal stem cells，BMSCs）在特定環境下能嚮骨、血管等組織細胞誘導分化，促進股骨頭壞死（osteonecrosis of the femeral head，ONFH）跼部新生血管的形成及壞死區骨組織的脩複替代，併具有易于穫得、增殖速度快、免疫原性低等優點，可作為組織工程優質種子細胞，在早期股骨頭壞死脩複方麵具有廣闊的臨床應用前景。本文就 BMSCs 治療早期 ONFH 的研究進展作一綜述。
골수간충질간세포（bone marrow mesenchymal stem cells，BMSCs）재특정배경하능향골、혈관등조직세포유도분화，촉진고골두배사（osteonecrosis of the femeral head，ONFH）국부신생혈관적형성급배사구골조직적수복체대，병구유역우획득、증식속도쾌、면역원성저등우점，가작위조직공정우질충자세포，재조기고골두배사수복방면구유엄활적림상응용전경。본문취 BMSCs 치료조기 ONFH 적연구진전작일종술。
ABSTRACT:Bone marrow mesenchymal stem cells (BMSCs)can differentiate into bone,blood vessel and other tissue cells under certain circumstances.Therefore,the transplantation of BMSCs can promote new blood vessel formation and repair necrotic bone tissue in the osteonecrosis of the femeral head.As ideal seed cells for tissue engineering,BMSCs have a wide prospect for clinical application in the repair of early-stage osteonecrosis of femoral head due to their advantages of easy obtainment,rapid proliferation and low immunogenicity.This paper reviews the research pro-gress in the treatment of early-stage osteonecrosis of femoral head with BMSCs.
