CAJ | 학술논문

目的：探讨血清视黄醇结合蛋白（RBP）水平在妊娠过程中变化，为科学指导不同孕期的孕妇控制营养水平提供实验室依据。方法选择182例在本院妇产科门诊行孕期体检和建卡分娩住院的孕妇，对按妊娠周数分为妊娠早、中、晚期组的孕妇进行 RBP 和传统营养状况评价指标前白蛋白（PA）、白蛋白（ALB）和血红蛋白（HGB）水平检测，与对照组（健康体检妇女）检测结果进行统计学分析，并对 RBP 在不同孕期中检出异常结果进行分析。结果妊娠早、中、晚期组 RBP 检测水平高于对照组，比较差异有统计学意义或高度统计学意义（P ＜0．05或 P ＜0．01）；妊娠早期组 PA、ALB 和 HGB 检测水平低于对照组，比较差异无统计学意义（P ＞0．05）；妊娠中、晚期组 PA、ALB 和 HGB 检测水平低于对照组，比较差异有统计学意义（P ＜0．05）。当孕妇机体的血容量发生明显变化时，血清 RBP 水平的变化趋势与孕妇营养状况有一致性。结论血清 RBP 是监测不同孕期的孕妇机体营养状况的良好指标，检测血清 RBP水平可为妊娠期内评价孕妇机体营养状况提供有价值的实验室依据。
목적：탐토혈청시황순결합단백（RBP）수평재임신과정중변화，위과학지도불동잉기적잉부공제영양수평제공실험실의거。방법선택182례재본원부산과문진행잉기체검화건잡분면주원적잉부，대안임신주수분위임신조、중、만기조적잉부진행 RBP 화전통영양상황평개지표전백단백（PA）、백단백（ALB）화혈홍단백（HGB）수평검측，여대조조（건강체검부녀）검측결과진행통계학분석，병대 RBP 재불동잉기중검출이상결과진행분석。결과임신조、중、만기조 RBP 검측수평고우대조조，비교차이유통계학의의혹고도통계학의의（P ＜0．05혹 P ＜0．01）；임신조기조 PA、ALB 화 HGB 검측수평저우대조조，비교차이무통계학의의（P ＞0．05）；임신중、만기조 PA、ALB 화 HGB 검측수평저우대조조，비교차이유통계학의의（P ＜0．05）。당잉부궤체적혈용량발생명현변화시，혈청 RBP 수평적변화추세여잉부영양상황유일치성。결론혈청 RBP 시감측불동잉기적잉부궤체영양상황적량호지표，검측혈청 RBP수평가위임신기내평개잉부궤체영양상황제공유개치적실험실의거。
Objective Discuss of serum retinol binding protein (RBP)level in pregnancy in the process of change, scientific guidance in different periods of pregnancy pregnant women nutritional level control to provide laboratory ba-sis.Methods Selection of 182 cases hospitalized in our hospital obstetrics and gynecology clinic for prenatal examina-tion and cards delivery of pregnant women,according to the gestation week number for early pregnancy,women in the late group RBP and traditional nutritional status evaluation index of Prealbumin (PA),albumin (ALB)and hemoglobin (HGB)water level test,and the control group (healthy women)testing results were statistically analyzed,and RBP in different pregnancy in testing of abnormal results were analyzed.Results Pregnancy early,middle and late group of RBP levels higher than the control group,the difference is statistically significant or highly significant (P <0.05 or P <0.01);pregnancy early PA,ALB,HGB level of detection is lower than that of the control group,the difference between no statistical significance (P >0.05);pregnancy,late group PA,ALB,HGB level of detection is lower than that of the control group,the difference has statistical significance (P < 0.05).When pregnant women body obvious changes in blood volume.Conclusion Serum RBP are good indicators of monitoring in different periods of pregnancy pregnant women nutritional status,serum levels of RBP level can provide valuable laboratory basis for the pregnancy period preg-nant women to evaluate the nutritional status of the body.The level of serum RBP trends are consistent with pregrant women to nutrition.