CAJ | 학술논문

目的：分析探讨盐酸氨溴索雾化吸入治疗小儿肺炎的临床效果。方法选择2013年1月至2014年4月来我院接受小儿肺炎治疗的患儿120例，将其按照年龄、性别等随机分为对照组和试验组，每组患儿60例.对照组患儿在常规治疗基础上加用雾化吸入糜蛋白酶治疗方式，试验组患儿在常规治疗基础上加用雾化吸入盐酸氨溴索治疗方式，比较两组患儿的治疗效果、临床症状消失时间以及不良反应发生率等情况。结果试验组患儿的治疗有效率为95.00%，对照组患儿的治疗有效率为78.33%，两组患儿比较差异显著，P<0.05具有统计学意义；试验组患儿的临床症状消失时间明显优于对照组患儿，两组患儿比较差异显著，P<0.05具有统计学意义；试验组患儿的不良反应发生率为20.00%，对照组患儿的不良反应发生率为38.33%，两组患儿比较差异显著，P<0.05具有统计学意义。结论采用雾化吸入盐酸氨溴索治疗小儿肺炎症状治疗效果显著，患儿的不良反应发生率低，且症状消失时间快，值得临床推广应用。
목적：분석탐토염산안추색무화흡입치료소인폐염적림상효과。방법선택2013년1월지2014년4월래아원접수소인폐염치료적환인120례，장기안조년령、성별등수궤분위대조조화시험조，매조환인60례.대조조환인재상규치료기출상가용무화흡입미단백매치료방식，시험조환인재상규치료기출상가용무화흡입염산안추색치료방식，비교량조환인적치료효과、림상증상소실시간이급불량반응발생솔등정황。결과시험조환인적치료유효솔위95.00%，대조조환인적치료유효솔위78.33%，량조환인비교차이현저，P<0.05구유통계학의의；시험조환인적림상증상소실시간명현우우대조조환인，량조환인비교차이현저，P<0.05구유통계학의의；시험조환인적불량반응발생솔위20.00%，대조조환인적불량반응발생솔위38.33%，량조환인비교차이현저，P<0.05구유통계학의의。결론채용무화흡입염산안추색치료소인폐염증상치료효과현저，환인적불량반응발생솔저，차증상소실시간쾌，치득림상추엄응용。
ObjectiveTo investigate the clinical effect of ambroxol hydrochloride inhalation in the treatment of pneumonia in children.Methods 120 cases from January 2013 to April 2014 was selected and randomly divided into control group and experiment group(n=60 each) in accordance with the age and gender. The former group were treated with chymotrypsin by nebulizer inhalation on the basis of conventional therapy and the experiment group were with atomizing inhalation of ambroxol hydrochloride treatment plus the conventional. Compare the clinical symptoms, disappearing time and adverse reaction rate between the two groups.ResultsThe effective rate of the experimental group was 95%, 78.33% in the control group. The difference was significant in the two groups, the clinical symptoms of the experimental group was significantly better than that in the control group. The difference was significant with satistical significance,P<0.05 and the disappearing time of experiment group is shorter than the other, significant difference(P<0.05); the incidence of adverse reactions in the experimental group was 20%, and the control group was 38.33%. The difference between the two groups was significant with statistical significanceP<0.05.The response lever of nasal mucosa in observation group is lower than the control group with the satistical significance(P<0.05). The complication rate of the observation group is lower than that of the control group with the satistical significance(P<0.05) Conclusion The method of ambroxol hydrochloride by nebulizer inhalation can treat infantile pneumonia well with low adverse reaction rate and shorter disappearing time, worthy of application.