中华实验和临床感染病杂志(电子版)
中華實驗和臨床感染病雜誌(電子版)
중화실험화림상감염병잡지(전자판)
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Version)
2015年
5期
689-692
,共4页
脑卒中%尿路感染%病原菌%药敏分析
腦卒中%尿路感染%病原菌%藥敏分析
뇌졸중%뇨로감염%병원균%약민분석
Stroke%Urinary tract infection%Pathogenic bacteria%Susceptibility testing
目的 分析脑卒中患者继发尿路感染的病原菌构成及药敏情况,为临床用药提供科学依据.方法 对2009年1月至2014年6月广饶县人民医院及滨州市中心医院神经内科收治的194例脑卒中并发尿路感染的患者病原菌构成及药敏结果,行回顾性分析和调查.结果 脑卒中继发尿路感染者的发生率为5.88%(207/3 518),共分离培养出各种病原菌194株,其中检出大肠埃希菌82株(占42.27%),肺炎克雷伯菌17株(8.76%),奇异变形杆菌10株(占5.15%),铜绿假单胞菌7株(占3.61%),表皮葡萄球菌18株(占9.28%),粪肠球菌10株(占5.15%),白色假丝酵母菌8株(占4.12%).大肠埃希菌对亚胺培南高度敏感,而左氧氟沙星则敏感性差(与左氧氟沙星相比,χ2 = 56.08、P< 0.01);对氨曲南高度敏感,而氨苄西林则敏感性差(与氨苄西林相比,χ2 = 108.57、P< 0.01),差异均具有统计学意义;同时对呋喃妥因及二、三代头孢也有较强的敏感性.结论 脑卒中继发尿路感染的病原菌构成以大肠埃希菌为最常见菌株,应加强监测,了解其对抗菌药物的敏感性,以期规范、合理使用抗菌药物,提高治疗效果.
目的 分析腦卒中患者繼髮尿路感染的病原菌構成及藥敏情況,為臨床用藥提供科學依據.方法 對2009年1月至2014年6月廣饒縣人民醫院及濱州市中心醫院神經內科收治的194例腦卒中併髮尿路感染的患者病原菌構成及藥敏結果,行迴顧性分析和調查.結果 腦卒中繼髮尿路感染者的髮生率為5.88%(207/3 518),共分離培養齣各種病原菌194株,其中檢齣大腸埃希菌82株(佔42.27%),肺炎剋雷伯菌17株(8.76%),奇異變形桿菌10株(佔5.15%),銅綠假單胞菌7株(佔3.61%),錶皮葡萄毬菌18株(佔9.28%),糞腸毬菌10株(佔5.15%),白色假絲酵母菌8株(佔4.12%).大腸埃希菌對亞胺培南高度敏感,而左氧氟沙星則敏感性差(與左氧氟沙星相比,χ2 = 56.08、P< 0.01);對氨麯南高度敏感,而氨芐西林則敏感性差(與氨芐西林相比,χ2 = 108.57、P< 0.01),差異均具有統計學意義;同時對呋喃妥因及二、三代頭孢也有較彊的敏感性.結論 腦卒中繼髮尿路感染的病原菌構成以大腸埃希菌為最常見菌株,應加彊鑑測,瞭解其對抗菌藥物的敏感性,以期規範、閤理使用抗菌藥物,提高治療效果.
목적 분석뇌졸중환자계발뇨로감염적병원균구성급약민정황,위림상용약제공과학의거.방법 대2009년1월지2014년6월엄요현인민의원급빈주시중심의원신경내과수치적194례뇌졸중병발뇨로감염적환자병원균구성급약민결과,행회고성분석화조사.결과 뇌졸중계발뇨로감염자적발생솔위5.88%(207/3 518),공분리배양출각충병원균194주,기중검출대장애희균82주(점42.27%),폐염극뢰백균17주(8.76%),기이변형간균10주(점5.15%),동록가단포균7주(점3.61%),표피포도구균18주(점9.28%),분장구균10주(점5.15%),백색가사효모균8주(점4.12%).대장애희균대아알배남고도민감,이좌양불사성칙민감성차(여좌양불사성상비,χ2 = 56.08、P< 0.01);대안곡남고도민감,이안변서림칙민감성차(여안변서림상비,χ2 = 108.57、P< 0.01),차이균구유통계학의의;동시대부남타인급이、삼대두포야유교강적민감성.결론 뇌졸중계발뇨로감염적병원균구성이대장애희균위최상견균주,응가강감측,료해기대항균약물적민감성,이기규범、합리사용항균약물,제고치료효과.
Objective To analyze the composition of pathogenic bacteria causing urinary tract infection (UTI) in patients with stroke and drug susceptibility testing, and to provide scientific basis for clinical medicine.Methods Total of 194 stoke patients with urinary tract infection (UTI) in Neurology Department of The People's Hospital of Guangrao County and The Center Hospital of Binzhou City from January 2009 to June 2014 were enrolled. The composition of pathogenic bacteria and drug susceptibility testing were investigated and analyzed, retrospectively.Results Urinary tract infection in patients with stroke incidence was 5.88% (207/3 518). Among the 194 strain pathogenic bacteria were isolated and cultured, including 82 (42.72%) stains ofE. coli, 17 (8.76%) stains ofKlebsiella pneumoniae, 10 (5.15%) strains of Proteus mirabilis, 7 (3.61%) strains ofPseudomonas aeruginosa, 18 (9.28%) staines ofStaphylococcus epidermidis, 10 (5.15%) strains ofEnterococcus faecalis, 8 (4.12%) strains ofWhite fake candida. E. coli were highly sensitive to imipenem, but poorly to levolfoxacin (χ2= 56.08,P < 0.01); and highly sensitive to aztreonam, but poorly to ampicillin (χ2= 108.57,P < 0.01), the difference were statistical signiifcance; while nitrofurantoin, the second and third generation cephalosporins also had strong sensitive toE. coli.Conclusions In the composition of pathogenic bacteria causing urinary tract infection with stroke patients.Escherichia coli was the most common strain, should strengthen the monitoring, to understand its susceptibility, in order to standardize, the rational use of antimicrobial drugs, improve the treatment effect.