CAJ | 학술논문

目的研究阴茎皮瓣尿道成形术治疗前尿道狭窄的长期疗效情况.方法选取2010年1月至2014年1月于本院接受治疗的80例前尿道狭窄患者,按数字表法随机将患者分为两组,每组各40例.其中观察组采用阴茎皮瓣尿道成形术进行治疗,对照组采用口腔黏膜尿道成形术进行治疗,观察并对比两组患者治疗后的远期疗效以及不良反应等情况.结果两组患者狭窄长度、术前治疗次数相比无显著性差异,在假性憩室方面观察组要显著低于对照组,差异有统计学意义(P＜0.05).两组患者手术时间、术中出血量、拔出尿管时间均无显著差异(P＜0.05);观察组皮瓣成活率达到100％明显高于对照组80.0％,患者拔除尿管时及术后3个月最大尿流率(MFR)、国际前列腺症状评分(IPSS)均明显优于对照组(P＜0.05);术后随访1年,观察组不良反应发生率明显低于对照组(P＜0.05);观察组患者治疗后1年QOL评分显著高于对照组,差异有统计学意义(P＜0.05).结论相对口腔黏膜尿道成形术,使用阴茎皮瓣尿道成形术治前尿道狭窄具有较为显著的疗效,患者远期恢复情况较好,且皮瓣成活率、不良反应情况均较少,是治疗前尿道狭窄十分有效的治疗方法.
목적 연구음경피판뇨도성형술치료전뇨도협착적장기료효정황.방법 선취2010년1월지2014년1월우본원접수치료적80례전뇨도협착환자,안수자표법수궤장환자분위량조,매조각40례.기중관찰조채용음경피판뇨도성형술진행치료,대조조채용구강점막뇨도성형술진행치료,관찰병대비량조환자치료후적원기료효이급불량반응등정황.결과 량조환자협착장도、술전치료차수상비무현저성차이,재가성게실방면관찰조요현저저우대조조,차이유통계학의의(P＜0.05).량조환자수술시간、술중출혈량、발출뇨관시간균무현저차이(P＜0.05);관찰조피판성활솔체도100％명현고우대조조80.0％,환자발제뇨관시급술후3개월최대뇨류솔(MFR)、국제전렬선증상평분(IPSS)균명현우우대조조(P＜0.05);술후수방1년,관찰조불량반응발생솔명현저우대조조(P＜0.05);관찰조환자치료후1년QOL평분현저고우대조조,차이유통계학의의(P＜0.05).결론 상대구강점막뇨도성형술,사용음경피판뇨도성형술치전뇨도협착구유교위현저적료효,환자원기회복정황교호,차피판성활솔、불량반응정황균교소,시치료전뇨도협착십분유효적치료방법.
Objectives To explore long-term efficacy of Penile skin flap urethroplasty surgery in the treatment of anterior urethral stricture.Methods From January 2010 to January 2014 in our hospital 80 cases of anterior urethral stricture patients,were randomly divided into two groups,40 cases in each group.The observation group with penis skin flap urethroplasty for treatment,control group with oral mucosaurethroplasty for treatment,observation of long term efficacy of the two groups after treatment and adverse reaction conditions.Results two groups of patients before treatment the symptom integral had no significant difference after treatment,the observation group were significantly lower than those in the control group,the difference was statistically significant,P ＜ 0.05;Two groups of patients with operation time,intraoperative bleeding volume,and there were no significant differences in the catheter time,P ＞0.05;The observation group the survival rate of 100％ was significantly higher than the control group of 80％ patients,the maximal urinary flow rate(MFR),the International Prostate Symptom Score (IPSS) was significantly better than the control group at 3 months and pulling out the catheter after operation,P ＜0.05;adverse reaction rate of observation group was significantly lower than the control group in the 1 years after the operation,P ＜ 0.05;Patients in the observation group 1 years after treatment QOL score was significantly higher than that of control group,difference had statistical significance,P ＜ 0.05.Conclusions For patients with penile skin flap urethroplasty in the treatment of anterior urethral stricture had more significant effect in patients with long-termrecovery,better than the oral mucosa urethroplasty,and the flap survival rate,adverse reactions are less,is the treatment of anterior urethral stricture treatment method is very effective.