国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
International Journal of Urology and Nephrology
2015年
6期
859-862
,共4页
包皮%波形蛋白%年龄因素
包皮%波形蛋白%年齡因素
포피%파형단백%년령인소
Foreskin%Vimentin%Age Factors
目的 探讨波形蛋白在不同年龄和形态包皮组织中的表达规律.方法 收集52例包皮标本中有包茎22例、包皮过长30例.用免疫组织化学方法检测包皮组织中波形蛋白的表达.结果 52例包皮组织中波形蛋白的表达呈弱阳性,其在包茎和包皮过长中表达差异无统计学意义(P>0.05).各年龄段中包茎和包皮过长之间波形蛋白的表达差异均无统计学意义(P>0.05).男子15岁以前包茎和包皮过长中波形蛋白的表达水平较15岁以后略高,差异有统计学意义(t=4.496、2.057,P=000、0.049).15岁以后包茎和单纯包皮过长中波形蛋白的表达水平开始下降.包茎与包皮过长组中波形蛋白的表达均与年龄呈负相关(r=-0.746、-0.288,P=0.000、0.123).结论 波形蛋白可能是参与形成不同形态包皮的重要因素,男子包皮组织中波形蛋白表达水平与年龄因素可能相关.
目的 探討波形蛋白在不同年齡和形態包皮組織中的錶達規律.方法 收集52例包皮標本中有包莖22例、包皮過長30例.用免疫組織化學方法檢測包皮組織中波形蛋白的錶達.結果 52例包皮組織中波形蛋白的錶達呈弱暘性,其在包莖和包皮過長中錶達差異無統計學意義(P>0.05).各年齡段中包莖和包皮過長之間波形蛋白的錶達差異均無統計學意義(P>0.05).男子15歲以前包莖和包皮過長中波形蛋白的錶達水平較15歲以後略高,差異有統計學意義(t=4.496、2.057,P=000、0.049).15歲以後包莖和單純包皮過長中波形蛋白的錶達水平開始下降.包莖與包皮過長組中波形蛋白的錶達均與年齡呈負相關(r=-0.746、-0.288,P=0.000、0.123).結論 波形蛋白可能是參與形成不同形態包皮的重要因素,男子包皮組織中波形蛋白錶達水平與年齡因素可能相關.
목적 탐토파형단백재불동년령화형태포피조직중적표체규률.방법 수집52례포피표본중유포경22례、포피과장30례.용면역조직화학방법검측포피조직중파형단백적표체.결과 52례포피조직중파형단백적표체정약양성,기재포경화포피과장중표체차이무통계학의의(P>0.05).각년령단중포경화포피과장지간파형단백적표체차이균무통계학의의(P>0.05).남자15세이전포경화포피과장중파형단백적표체수평교15세이후략고,차이유통계학의의(t=4.496、2.057,P=000、0.049).15세이후포경화단순포피과장중파형단백적표체수평개시하강.포경여포피과장조중파형단백적표체균여년령정부상관(r=-0.746、-0.288,P=0.000、0.123).결론 파형단백가능시삼여형성불동형태포피적중요인소,남자포피조직중파형단백표체수평여년령인소가능상관.
Objectives To investigate the expression of vimentin in prepuce of different shapes and ages.Methods Totally 52 samples of prepuce were recorded with 22 of phimosis and 30 of abundant prepuce.The expression of vimentin was detected in all samples of prepuce by immunohistochemistry.Results Expression of vimentin in 52 cases in the prepuce was weakly positive,between the phimosis and redundant prepuce,there was no significant difference in the expression(P >0.05).The expression of vimentin between phimosis and redundant prepuce in all age groups was not statistically significant(P >0.05).The expression level of vimentin phimosis and redundant prepuce in the man before the age of 15 was slightly higher than those of who were after the age of 15,there were significant difference(t =4.496、2.057,P =000、0.049).After the age of 15,the expression of vimentin in phimosis and abundant prepuce decreased.The expression of vimentin in phimosis and redundant prepuce was negatively correlated with the aging factor(r =-0.746、-0.288,P =0.000、0.123).Conclusions Vimentin might play an important role in the formation of different shapes of prepuce,the level of vimentin expression in prepuce might be related to the aging factor of males.