国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
International Journal of Urology and Nephrology
2015年
6期
899-902
,共4页
张丽%张然%田领%勾艳丽%于征%张继伟
張麗%張然%田領%勾豔麗%于徵%張繼偉
장려%장연%전령%구염려%우정%장계위
肾功能衰竭,慢性%心力衰竭%利钠肽,脑%C反应蛋白质
腎功能衰竭,慢性%心力衰竭%利鈉肽,腦%C反應蛋白質
신공능쇠갈,만성%심력쇠갈%리납태,뇌%C반응단백질
Kidney Failure,Chronic%Heart Failure%Natriuretic Peptide,Brain%C-Reactive Protein
目的 探讨脑钠肽(BNP)及C-反应蛋白(CRP)在慢性肾衰竭(CRF)合并慢性心力衰竭(CHF)患者的诊断和判断预后的意义.方法 选取CRF合并CHF患者69例作为观察组,单纯CHF患者40例作为对照组A,再选取同期健康体检者40例作为对照组B,分别检测并对比三组受试者治疗前后BNP、CRP水平及观察组患者治疗前后不同CKD分期、NYHA分级时BNP、CRP水平变化.结果 观察组、对照组A患者治疗前BNP、CRP水平明显高于对照组B,差异具有显著性(P＜0.05),观察组、对照组A患者经2周治疗后BNP、CRP水平较治疗前显著降低,差异具有显著性(P＜0.05),观察组患者治疗后及对照组A患者治疗后BNP、CRP与对照组B差异无显著性(P＞0.05),观察组患者比较治疗前后BNP、CRP水平随NYHA分级的升高而明显增高(P＜0.05),与CKD分期增高无相关关系(P＞0.05).结论 血浆BNP、CRP水平变化在慢性肾衰竭(CRF)合并慢性心力衰竭(CHF)患者的诊断、疗效评价和判断预后具有重要临床价值.
目的 探討腦鈉肽(BNP)及C-反應蛋白(CRP)在慢性腎衰竭(CRF)閤併慢性心力衰竭(CHF)患者的診斷和判斷預後的意義.方法 選取CRF閤併CHF患者69例作為觀察組,單純CHF患者40例作為對照組A,再選取同期健康體檢者40例作為對照組B,分彆檢測併對比三組受試者治療前後BNP、CRP水平及觀察組患者治療前後不同CKD分期、NYHA分級時BNP、CRP水平變化.結果 觀察組、對照組A患者治療前BNP、CRP水平明顯高于對照組B,差異具有顯著性(P＜0.05),觀察組、對照組A患者經2週治療後BNP、CRP水平較治療前顯著降低,差異具有顯著性(P＜0.05),觀察組患者治療後及對照組A患者治療後BNP、CRP與對照組B差異無顯著性(P＞0.05),觀察組患者比較治療前後BNP、CRP水平隨NYHA分級的升高而明顯增高(P＜0.05),與CKD分期增高無相關關繫(P＞0.05).結論 血漿BNP、CRP水平變化在慢性腎衰竭(CRF)閤併慢性心力衰竭(CHF)患者的診斷、療效評價和判斷預後具有重要臨床價值.
목적 탐토뇌납태(BNP)급C-반응단백(CRP)재만성신쇠갈(CRF)합병만성심력쇠갈(CHF)환자적진단화판단예후적의의.방법 선취CRF합병CHF환자69례작위관찰조,단순CHF환자40례작위대조조A,재선취동기건강체검자40례작위대조조B,분별검측병대비삼조수시자치료전후BNP、CRP수평급관찰조환자치료전후불동CKD분기、NYHA분급시BNP、CRP수평변화.결과 관찰조、대조조A환자치료전BNP、CRP수평명현고우대조조B,차이구유현저성(P＜0.05),관찰조、대조조A환자경2주치료후BNP、CRP수평교치료전현저강저,차이구유현저성(P＜0.05),관찰조환자치료후급대조조A환자치료후BNP、CRP여대조조B차이무현저성(P＞0.05),관찰조환자비교치료전후BNP、CRP수평수NYHA분급적승고이명현증고(P＜0.05),여CKD분기증고무상관관계(P＞0.05).결론 혈장BNP、CRP수평변화재만성신쇠갈(CRF)합병만성심력쇠갈(CHF)환자적진단、료효평개화판단예후구유중요림상개치.
Objectives the level difference of plasma BNP and CRP is of significant clinical value in the treatment,the therapeutic evaluation and the anticipation prognosis of the patients with CRF and CHF.Methods The method of to select 69 patients with CRF and CHF as the observing team,in contrast to the team A of 40 patients with CHF only,team B of the healthy check-up,comparing the level difference of BNP and CRP of the patients in these three groups before and after treatment.Results As a result,the BNP and CRP level is much higher in observing team and team A than in team B,and the difference is significant (P ＜ 0.05);while after two-week treatment,they have increasingly lowered,the difference is distinctive (P ＜0.05).The difference of the patients in group A and observing is not significant(P ＞0.05),and the level of BNP and CRP of these two groups has remarkably increased with the classification of NYHA (P ＜ 0.05),irrelevant to the increasing CKD(P ＞ 0.05).Conclusions The level difference of plasma BNP and CRP is of significant clinical value in the treatment,the therapeutic evaluation and the anticipation prognosis of the patients with CRF and CHF.
