中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Version)
2015年
5期
621-624
,共4页
人类免疫缺陷病毒%gp120蛋白%骨代谢%骨质疏松
人類免疫缺陷病毒%gp120蛋白%骨代謝%骨質疏鬆
인류면역결함병독%gp120단백%골대사%골질소송
Human immunodeifciency virus%gp120%Bone metabolism%Osteoporosis
HIV感染人群骨量减少和骨质疏松的发生率远高于普通人群.HIV感染人群患骨质疏松和骨量减少的危险因素,除了一般人群面对的危险因素之外,还包括病毒本身、抗病毒药物等危险因素.其中,gp120对骨代谢的影响是HIV病毒本身引起骨质疏松的重要机制之一.本文将对gp120的前期研究进行总结,便于深入研究HIV病毒本身对骨代谢的影响.
HIV感染人群骨量減少和骨質疏鬆的髮生率遠高于普通人群.HIV感染人群患骨質疏鬆和骨量減少的危險因素,除瞭一般人群麵對的危險因素之外,還包括病毒本身、抗病毒藥物等危險因素.其中,gp120對骨代謝的影響是HIV病毒本身引起骨質疏鬆的重要機製之一.本文將對gp120的前期研究進行總結,便于深入研究HIV病毒本身對骨代謝的影響.
HIV감염인군골량감소화골질소송적발생솔원고우보통인군.HIV감염인군환골질소송화골량감소적위험인소,제료일반인군면대적위험인소지외,환포괄병독본신、항병독약물등위험인소.기중,gp120대골대사적영향시HIV병독본신인기골질소송적중요궤제지일.본문장대gp120적전기연구진행총결,편우심입연구HIV병독본신대골대사적영향.
The incidence of bone mass loss and osteoporosis is superior in HIV infection people than in ordinary crowd. The risk factors for bone mass loss and osteoporosis in HIV infected people include HIV itself, Antiviral agents etc, in addition to the risk factors the ordinary crowd face. The expression of gp120 on bone metabolism is one of the important mechanisms of osteoporosis caused by HIV itself. This review summarized the progress in the impression and mechanism of human immunodeficiency virus envelope glycoprotein gp120 on bone metabolism, in order to facilitate further study of the effects of HIV itself to bone metabolism.
