CAJ | 학술논문

肝功能衰竭是由于多种因素引起的肝脏严重损害,其并发症多、病情进展快,预后极差.如何准确评估预后、指导临床制定合理的治疗方案是治疗的关键问题.目前应用较多的评估系统主要有:Child-Turotte-Pugh评分、终末期肝病模型、英国皇家医学院医院标准,急性生理、年龄和慢性健康评分和序贯器官衰竭评估等.近年来,一些反映肝功能衰竭预后的新兴生物标志物不断出现,显示了潜在的评估价值.本文对肝功能衰竭预后评估的研究进展作一综述.
간공능쇠갈시유우다충인소인기적간장엄중손해,기병발증다、병정진전쾌,예후겁차.여하준학평고예후、지도림상제정합리적치료방안시치료적관건문제.목전응용교다적평고계통주요유:Child-Turotte-Pugh평분、종말기간병모형、영국황가의학원의원표준,급성생리、년령화만성건강평분화서관기관쇠갈평고등.근년래,일사반영간공능쇠갈예후적신흥생물표지물불단출현,현시료잠재적평고개치.본문대간공능쇠갈예후평고적연구진전작일종술.
Liver failure is serious liver damages characterized by many complications, rapid progression and poor prognosis. How to accurately predict the prognosis and guide treatment is the key problem. The assessment systems widely used include Child-Turotte-Pugh (CTP) score, model for end-stage liver disease (MELD), King's College Hospital (KCH) criteria, acute physiology, age and chronic health evaluation (APACHE) and sequential organ failure assessment (SOFA). Recently, a variety of emerging biomarkers showed potential values for prognosis assessment. This paper reviews on current progresses of prognosis assessment in liver failure.