中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Version)
2015年
5期
640-642
,共3页
血清降钙素原%医院感染%抗菌药物%医院感染%管理
血清降鈣素原%醫院感染%抗菌藥物%醫院感染%管理
혈청강개소원%의원감염%항균약물%의원감염%관리
Procalcitonin%Hospital infection%Antibiotic%Hospital infection%Management
目的 探讨根据血清降钙素原(PCT)检测结果诊治、管理医院感染的价值.方法 将227例呼吸道医院感染者随机分为对照组107例(据症状、体征和WBC等决定抗菌药物使用)和观察组120例(在对照组基础上检测PCT决定是否、如何应用抗菌药物).比较两组患者的诊治转归、抗菌药物使用、诊治费用及医院感染管理指标.结果 观察组患者PCT水平正常者占47.5%、升高者占52.5%;观察组患者抗菌药物使用率显著低于对照组(52.5% vs 96.3%,χ2= 4.848,P< 0.01),院感后治疗检查费显著增加[(735 ± 97)元 vs(1 502 ± 185)元;t = 4.604,P< 0.01];两组患者均全部治愈.PCT应用前、后院感病例管理两个关键指标:病原学送检率分别为(31 ± 10)%和(86 ± 12)%(t = 4.603、P< 0.01),抗菌药物使用率分别为(92 ± 7)%和(40 ± 10)%(t= 3.706、P< 0.01).结论 观察组抗菌药物使用率和医疗费用增长幅度均显著减少,PCT检测指导医院感染诊治能够显著改善管理指标.
目的 探討根據血清降鈣素原(PCT)檢測結果診治、管理醫院感染的價值.方法 將227例呼吸道醫院感染者隨機分為對照組107例(據癥狀、體徵和WBC等決定抗菌藥物使用)和觀察組120例(在對照組基礎上檢測PCT決定是否、如何應用抗菌藥物).比較兩組患者的診治轉歸、抗菌藥物使用、診治費用及醫院感染管理指標.結果 觀察組患者PCT水平正常者佔47.5%、升高者佔52.5%;觀察組患者抗菌藥物使用率顯著低于對照組(52.5% vs 96.3%,χ2= 4.848,P< 0.01),院感後治療檢查費顯著增加[(735 ± 97)元 vs(1 502 ± 185)元;t = 4.604,P< 0.01];兩組患者均全部治愈.PCT應用前、後院感病例管理兩箇關鍵指標:病原學送檢率分彆為(31 ± 10)%和(86 ± 12)%(t = 4.603、P< 0.01),抗菌藥物使用率分彆為(92 ± 7)%和(40 ± 10)%(t= 3.706、P< 0.01).結論 觀察組抗菌藥物使用率和醫療費用增長幅度均顯著減少,PCT檢測指導醫院感染診治能夠顯著改善管理指標.
목적 탐토근거혈청강개소원(PCT)검측결과진치、관리의원감염적개치.방법 장227례호흡도의원감염자수궤분위대조조107례(거증상、체정화WBC등결정항균약물사용)화관찰조120례(재대조조기출상검측PCT결정시부、여하응용항균약물).비교량조환자적진치전귀、항균약물사용、진치비용급의원감염관리지표.결과 관찰조환자PCT수평정상자점47.5%、승고자점52.5%;관찰조환자항균약물사용솔현저저우대조조(52.5% vs 96.3%,χ2= 4.848,P< 0.01),원감후치료검사비현저증가[(735 ± 97)원 vs(1 502 ± 185)원;t = 4.604,P< 0.01];량조환자균전부치유.PCT응용전、후원감병례관리량개관건지표:병원학송검솔분별위(31 ± 10)%화(86 ± 12)%(t = 4.603、P< 0.01),항균약물사용솔분별위(92 ± 7)%화(40 ± 10)%(t= 3.706、P< 0.01).결론 관찰조항균약물사용솔화의료비용증장폭도균현저감소,PCT검측지도의원감염진치능구현저개선관리지표.
Objective To investigate the value of the diagnosis-treatment and management of hospital infection according to the testing results of serum PCT.Methods Total of 227 patients with respiratory tract nosocomial infection were randomly divided into two groups. The control group with 107 cases were decided to use antibiotic by the symptoms, signs and the WBC. The observation group with 120 cases were decided whether and how to use of antibiotics by detection of PCT based on the control group. Treatment outcome, antibiotic use, diagnosis-treatment costs and the parameters of hospital infection management were compared between two groups, respectively.Results The normal or higher levels of PCT in observation group were 47.5% and 52.5%. The usage rate of antibiotics in observation group signiifcant lower than the control group (52.5% vs 96.3%;χ2= 4.848,P < 0.01), and the medical fee increased signiifcantly (735 ± 97 yuan vs 1 502 ± 185 yuan;t = 4.604,P < 0.01). Patients in the two groups were all cured. The two key indicators of the hospital infection management before and after PCT application: the etiology inspection rate were (31 ± 10)% vs (86 ± 12)% (t= 4.603, P < 0.01); antibiotics usage rate were (92 ± 7)% vs (40 ± 10)% (t= 3.706, P< 0.01).Conclusions The antibiotic utilization rates and medical fee increasing in PCT group were signiifcantly reduced. It could signiifcantly improve the management index of hospital infection instructed by PCT test.
