CAJ | 학술논문

目的：分别采用Excel和CMRtools（2012）软件计算重型β地中海贫血患者的T2*值，探讨两者评价铁过载患者T2*值的一致性和可替代性。资料与方法将27例重型β地中海贫血患者的T2*图像直接导入CMRtools（2012），在图像上勾画感兴趣区，去除干扰信号后直接计算出T2*值；在MRI自带软件中测量T2*图像感兴趣区的信号值，手工输入Excel中，去除干扰信号后计算出T2*值，比较两种方法测量肝脏及心肌铁过载T2*值的差异。结果27例重型β地中海贫血患者中，心肌铁过载10例，肝脏铁过载25例。Excel和CMRtools（2012）软件计算的心肌及肝脏T2*值差异无统计学意义（t=－0.152、－0.691，P>0.05）。结论 Excel和CMRtools（2012）软件在评价铁过载患者的T2*值方面具有很好的一致性，临床上可以应用Excel评价重型β地中海贫血患者的铁过载情况。
목적：분별채용Excel화CMRtools（2012）연건계산중형β지중해빈혈환자적T2*치，탐토량자평개철과재환자T2*치적일치성화가체대성。자료여방법장27례중형β지중해빈혈환자적T2*도상직접도입CMRtools（2012），재도상상구화감흥취구，거제간우신호후직접계산출T2*치；재MRI자대연건중측량T2*도상감흥취구적신호치，수공수입Excel중，거제간우신호후계산출T2*치，비교량충방법측량간장급심기철과재T2*치적차이。결과27례중형β지중해빈혈환자중，심기철과재10례，간장철과재25례。Excel화CMRtools（2012）연건계산적심기급간장T2*치차이무통계학의의（t=－0.152、－0.691，P>0.05）。결론 Excel화CMRtools（2012）연건재평개철과재환자적T2*치방면구유흔호적일치성，림상상가이응용Excel평개중형β지중해빈혈환자적철과재정황。
PurposeTo assess the level of agreement and interchangeability among Excel and CMRtools (2012) for calculation of T2* values in iron overload.Materials and Methods T2* images in 27 cases withβ-thalassemia major were imported into CMRtools (2012). The regions of interest (ROI) were drawn and interference signal removed to obtain T2* values. The T2* images were also measured using default MR software and manually entered into Excel to obtain T2* values after removal of the interference signal. The agreement between the two methods in calculating T2* values was compared.Results For 27 patients withβ-thalassemia major, 10 cases showed myocardial iron overload. 25 cases had liver iron overload. The T2* values from two methods were not statistically significant (t=-0.152 and-0.691,P>0.05) for the liver.Conclusion There is good agreement and interchangeability between Excel and CMRtools (2012) in calculating T2* values. Excel can be used clinically to evaluate iron overload.