重庆医学
重慶醫學
중경의학
Chongqing Medicine
2015年
31期
4336-4337,4342
,共3页
肝肿瘤%导管消融术%手术%治疗结果
肝腫瘤%導管消融術%手術%治療結果
간종류%도관소융술%수술%치료결과
liver neoplasms%catheter ablation%surgery%treatment outcome
目的:探讨两种不同治疗方法针对单发肿瘤直径介于3~6 cm的肝癌疗效,为临床治疗方式的选择提供依据。方法回顾性分析2008年12月至2011年12月期间在第三军医大学西南医院全军肝胆外科研究所接受手术切除或射频消融治疗单发肿瘤直径介于3~6 cm肝癌的近、远期疗效,比较两种手术方式的疗效差异。结果手术组术后1年以内复发41例,复发率为32.5%,2年以内复发87例,复发率为69.1%,3年以内复发103例,复发率为81.7%,射频消融组术后1年内复发29例,复发率为40.8%,2年以内复发51例,复发率为71.8%,3年以内复发60例,复发率为84.5%,二者之间同时间段复发率差异有统计学意义( P=0.039);手术组存活率第1、2、3年内分别为84.6%,69.8%,56.3%,射频消融组存活率第1、2、3年内分别为85.3%,70.9%,53.4%,二者同时间段存活率差异无统计学意义( P=0.105)。结论针对大小介于3~6 cm的单发性肝癌,射频消融治疗可作为首选治疗方法。
目的:探討兩種不同治療方法針對單髮腫瘤直徑介于3~6 cm的肝癌療效,為臨床治療方式的選擇提供依據。方法迴顧性分析2008年12月至2011年12月期間在第三軍醫大學西南醫院全軍肝膽外科研究所接受手術切除或射頻消融治療單髮腫瘤直徑介于3~6 cm肝癌的近、遠期療效,比較兩種手術方式的療效差異。結果手術組術後1年以內複髮41例,複髮率為32.5%,2年以內複髮87例,複髮率為69.1%,3年以內複髮103例,複髮率為81.7%,射頻消融組術後1年內複髮29例,複髮率為40.8%,2年以內複髮51例,複髮率為71.8%,3年以內複髮60例,複髮率為84.5%,二者之間同時間段複髮率差異有統計學意義( P=0.039);手術組存活率第1、2、3年內分彆為84.6%,69.8%,56.3%,射頻消融組存活率第1、2、3年內分彆為85.3%,70.9%,53.4%,二者同時間段存活率差異無統計學意義( P=0.105)。結論針對大小介于3~6 cm的單髮性肝癌,射頻消融治療可作為首選治療方法。
목적:탐토량충불동치료방법침대단발종류직경개우3~6 cm적간암료효,위림상치료방식적선택제공의거。방법회고성분석2008년12월지2011년12월기간재제삼군의대학서남의원전군간담외과연구소접수수술절제혹사빈소융치료단발종류직경개우3~6 cm간암적근、원기료효,비교량충수술방식적료효차이。결과수술조술후1년이내복발41례,복발솔위32.5%,2년이내복발87례,복발솔위69.1%,3년이내복발103례,복발솔위81.7%,사빈소융조술후1년내복발29례,복발솔위40.8%,2년이내복발51례,복발솔위71.8%,3년이내복발60례,복발솔위84.5%,이자지간동시간단복발솔차이유통계학의의( P=0.039);수술조존활솔제1、2、3년내분별위84.6%,69.8%,56.3%,사빈소융조존활솔제1、2、3년내분별위85.3%,70.9%,53.4%,이자동시간단존활솔차이무통계학의의( P=0.105)。결론침대대소개우3~6 cm적단발성간암,사빈소융치료가작위수선치료방법。
Objective To investigate the efficacy of two different methods in treatment of liver cancer which sizes ranged from 3 to 6cm ,and provide the basis for clinical treatment methods .Methods A retrospective analysis of the curative effect of liver cancer patients whose tumor diameter were rang from 3 to 6 cm was done .All patients collected from the Forth Cadre′s Sanatorium and Health Center ,Military Region in Shandong province Taian zones at the time of December 2008 to December 2011 who carried out surgical resection or radiofrequency ablation .Results 41 cases of recurrence within a year in surgical group ,the recurrence rate was 32 .5% ,87 cases(69 .1% ) of recurrence ,103 cases(81 .7% ) of recurrence within 3 years ;41 cases of recurrence within a year in radio frequency ablation group ,the recurrence rate was 40 .8% ,51 cases(71 .8% ) of recurrence within 2 years ,60 cases(84 .5% ) of recurrence within 3 years ,a statistically significant difference were found between the two group at the same period time (P<0 .05);1 ,2 ,3 year survival rates were 84 .6% ,69 .8% ,56 .3% in surgical group ,radiofrequency 1 ,2 ,3 year survival rates were 85 .3% ,70 .9% ,53 .4 in radio frequency ablation group ,The difference was not statistically significant at the same period time (P>0 .05) .Conclusion For size between 3 to 6 cm liver cancer ,radiofrequency ablation can be used as the preferred method of treatment .