CAJ | 학술논문

目的：调查克拉玛依地区维吾尔族和汉族健康成人的CD3＋、CD4＋、CD8＋计数及CD4＋／CD8＋比值，为该地区相关疾病的诊断、治疗及预后指导提供依据。方法选取181例健康成人，留取静脉全血，采用细胞芯片定量检测技术检测CD3＋、CD4＋、CD8＋细胞，比较维吾尔族与汉族健康成人 CD3＋、CD4＋、CD8＋绝对值和 CD4＋／CD8＋比值的参考范围。结果除了CD8＋计数均值和CD4＋／CD8＋比值在两族间差异无统计学意义（ P＞0．05）外，CD3＋、CD4＋计数均值在维吾尔族和汉族间差异均有统计学意义（P＜0．05）。结论 CD4＋诊疗标准的设立应重视地域和生活环境的差异，按种族设立不同正常参考值范围对诊断疾病有较大意义。
목적：조사극랍마의지구유오이족화한족건강성인적CD3＋、CD4＋、CD8＋계수급CD4＋／CD8＋비치，위해지구상관질병적진단、치료급예후지도제공의거。방법선취181례건강성인，류취정맥전혈，채용세포심편정량검측기술검측CD3＋、CD4＋、CD8＋세포，비교유오이족여한족건강성인 CD3＋、CD4＋、CD8＋절대치화 CD4＋／CD8＋비치적삼고범위。결과제료CD8＋계수균치화CD4＋／CD8＋비치재량족간차이무통계학의의（ P＞0．05）외，CD3＋、CD4＋계수균치재유오이족화한족간차이균유통계학의의（P＜0．05）。결론 CD4＋진료표준적설립응중시지역화생활배경적차이，안충족설립불동정상삼고치범위대진단질병유교대의의。
Objective To built the reference range of peripheral blood T-lymphocyte subsets including CD3+ ,CD4+ ,CD8+ and CD4+ /CD8+ ratio in healthy adults of Ugyur and Han nationalities and to provide basis for the diagnosis ,therapy and prognosis of disease .Methods A total of 181 blood samples were collected from healthy adults .The cell chip quantitative detection technology was used to detect CD3+ ,CD4+ and CD8+ ,CD3+ ,CD4+ absolute value ,CD8+ and CD4+ /CD8+ ratio were compared between Ugyur and Han nationalities .Results CD8+ absolute counting and CD4+ /CD8+ ratio had no significant difference between Ugyur and Han nationalities(P>0 .05) ,while the CD3+ ,CD4+ absolute counting had significant difference(P<0 .05) .Conclusion The discrepancy of territory and living environment should be taken into account for building a reference values of CD4+ .