重庆医学
重慶醫學
중경의학
Chongqing Medicine
2015年
32期
4527-4528,4531
,共3页
心肌梗死%尿纤溶酶原激活物%丹参多酚酸盐%溶栓
心肌梗死%尿纖溶酶原激活物%丹參多酚痠鹽%溶栓
심기경사%뇨섬용매원격활물%단삼다분산염%용전
myocardial infarction%urinary plasminogen activator%salvia miltiorrhiza salt%thrombolytic therapy
目的：观察丹参多酚酸盐联合尿激酶治疗急性S T段抬高型心肌梗死后心绞痛的疗效及安全性。方法将124例患者分成治疗组和对照组，每组62例。两组均给予冠心病二级预防治疗及溶栓治疗（尿激酶150万U溶于生理盐水100 m L中30 min内滴完），随后对照组给予极化液治疗，治疗组给予丹参多酚酸盐200 mg稀释于5％葡萄糖或生理盐水250 mL中静脉滴注15 d。观察两组心肌梗死后心绞痛发生情况、疗效及安全性。结果治疗组心绞痛发生率为25．81％，对照组心绞痛发生率为56．45％，两组比较差异有统计学意义（ P＜0．05）。结论应用丹参多酚酸盐联合尿激酶治疗急性S T段抬高型心肌梗死，可以显著减少心肌梗死后心绞痛，临床疗效好，不良反应少，安全性好。
目的：觀察丹參多酚痠鹽聯閤尿激酶治療急性S T段抬高型心肌梗死後心絞痛的療效及安全性。方法將124例患者分成治療組和對照組，每組62例。兩組均給予冠心病二級預防治療及溶栓治療（尿激酶150萬U溶于生理鹽水100 m L中30 min內滴完），隨後對照組給予極化液治療，治療組給予丹參多酚痠鹽200 mg稀釋于5％葡萄糖或生理鹽水250 mL中靜脈滴註15 d。觀察兩組心肌梗死後心絞痛髮生情況、療效及安全性。結果治療組心絞痛髮生率為25．81％，對照組心絞痛髮生率為56．45％，兩組比較差異有統計學意義（ P＜0．05）。結論應用丹參多酚痠鹽聯閤尿激酶治療急性S T段抬高型心肌梗死，可以顯著減少心肌梗死後心絞痛，臨床療效好，不良反應少，安全性好。
목적：관찰단삼다분산염연합뇨격매치료급성S T단태고형심기경사후심교통적료효급안전성。방법장124례환자분성치료조화대조조，매조62례。량조균급여관심병이급예방치료급용전치료（뇨격매150만U용우생리염수100 m L중30 min내적완），수후대조조급여겁화액치료，치료조급여단삼다분산염200 mg희석우5％포도당혹생리염수250 mL중정맥적주15 d。관찰량조심기경사후심교통발생정황、료효급안전성。결과치료조심교통발생솔위25．81％，대조조심교통발생솔위56．45％，량조비교차이유통계학의의（ P＜0．05）。결론응용단삼다분산염연합뇨격매치료급성S T단태고형심기경사，가이현저감소심기경사후심교통，림상료효호，불량반응소，안전성호。
Objective To compare the curative effect and safety of salvia miltiorrhiza salt combined with urokinase and sim‐ple application of urokinase in the treatment of angina pectoris after thrombolysis of acute ST‐elevation myocardial infarction .Meth‐ods Totally 124 cases patients were random divided into treatment group and control group ,62 cases in each group ,two group were given coronary heart disease Ⅱ level prevention treatment and dissolved tied treatment (urine kinase 1 .5 million U dissolved Yu saline 100 mL in the 30 minutes within drops finished ,only with a times) ,then control group was given polarization liquid treat‐ment ,treatment group was given Salvia more phenol acid salt 200 mg diluted Yu 5% glucose or saline 250 mL in the vein drops note 15 days ,incidence of myocardial infarction and angina pectoris and drug side effects were observed .Results Incidence of angina pectoris was 25 .81% in the treatment group and control group was 56 .45% ,there were significant differences in the two groups (P<0 .05) .Conclusion Application of phenolic acids from salvia miltiorrhiza salt combined with urokinase in the treatment of a‐cute ST‐elevation myocardial infarction ,myocardial infarction and angina pectoris can be significantly reduced ,and with good clinical efficacy and fewer side effects ,and it is safety .
