风湿病与关节炎
風濕病與關節炎
풍습병여관절염
Rheumatism and Arthritis
2015年
11期
23-25,28
,共4页
关节炎,类风湿%流行病学%临床%调查%遵义市
關節炎,類風濕%流行病學%臨床%調查%遵義市
관절염,류풍습%류행병학%림상%조사%준의시
arthritis,rheumatoid%Epidemiology%clinic%investigation%Zunyi City
目的：回顾性分析遵义市类风湿关节炎住院患者的临床资料，寻找其临床特点，为类风湿关节炎的诊断、治疗提供更多的临床依据。方法：回顾性分析2008年2月至2013年12月在遵义市第一人民医院住院的类风湿关节炎患者的临床病历资料，并统计分析患者的一般情况和实验室指标。结果：共收集第一诊断为类风湿关节炎的患者320例，男68例，女252例。职业特点：职员106例，农民144例，工人34例，无业36例。居住环境：城市146例，农村156例，城乡结合18例。合并感染患者65例，其中肺部感染48例，泌尿系感染17例。吸烟情况：吸烟52例，男44例，女8例。实验室检查结果：类风湿因子阳性288例，抗 CCP 抗体阳性255例，C-反应蛋白增高186例，红细胞沉降率升高258例，血小板升高125例，贫血158例，总蛋白降低102例，清蛋白降低214例，三酰甘油增高49例，胆固醇增高3例，高密度脂蛋白降低101例，低密度脂蛋白增高56例。Logistic 回归结果：类风湿关节炎贫血与血清清蛋白降低相关，炎症活动性指标红细胞沉降率、C-反应蛋白与血清清蛋白、血小板呈负相关。结论：遵义市类风湿关节炎患病率女性较高，以农民为主，但无明显居住地域性差异。住院患者多为病变的急性期，多合并低蛋白血症、贫血及血脂代谢异常。患者合并感染占20%，以肺部间质性病变为主。吸烟可能是遵义市男性 RA 患者发病的危险因素之一。
目的：迴顧性分析遵義市類風濕關節炎住院患者的臨床資料，尋找其臨床特點，為類風濕關節炎的診斷、治療提供更多的臨床依據。方法：迴顧性分析2008年2月至2013年12月在遵義市第一人民醫院住院的類風濕關節炎患者的臨床病歷資料，併統計分析患者的一般情況和實驗室指標。結果：共收集第一診斷為類風濕關節炎的患者320例，男68例，女252例。職業特點：職員106例，農民144例，工人34例，無業36例。居住環境：城市146例，農村156例，城鄉結閤18例。閤併感染患者65例，其中肺部感染48例，泌尿繫感染17例。吸煙情況：吸煙52例，男44例，女8例。實驗室檢查結果：類風濕因子暘性288例，抗 CCP 抗體暘性255例，C-反應蛋白增高186例，紅細胞沉降率升高258例，血小闆升高125例，貧血158例，總蛋白降低102例，清蛋白降低214例，三酰甘油增高49例，膽固醇增高3例，高密度脂蛋白降低101例，低密度脂蛋白增高56例。Logistic 迴歸結果：類風濕關節炎貧血與血清清蛋白降低相關，炎癥活動性指標紅細胞沉降率、C-反應蛋白與血清清蛋白、血小闆呈負相關。結論：遵義市類風濕關節炎患病率女性較高，以農民為主，但無明顯居住地域性差異。住院患者多為病變的急性期，多閤併低蛋白血癥、貧血及血脂代謝異常。患者閤併感染佔20%，以肺部間質性病變為主。吸煙可能是遵義市男性 RA 患者髮病的危險因素之一。
목적：회고성분석준의시류풍습관절염주원환자적림상자료，심조기림상특점，위류풍습관절염적진단、치료제공경다적림상의거。방법：회고성분석2008년2월지2013년12월재준의시제일인민의원주원적류풍습관절염환자적림상병력자료，병통계분석환자적일반정황화실험실지표。결과：공수집제일진단위류풍습관절염적환자320례，남68례，녀252례。직업특점：직원106례，농민144례，공인34례，무업36례。거주배경：성시146례，농촌156례，성향결합18례。합병감염환자65례，기중폐부감염48례，비뇨계감염17례。흡연정황：흡연52례，남44례，녀8례。실험실검사결과：류풍습인자양성288례，항 CCP 항체양성255례，C-반응단백증고186례，홍세포침강솔승고258례，혈소판승고125례，빈혈158례，총단백강저102례，청단백강저214례，삼선감유증고49례，담고순증고3례，고밀도지단백강저101례，저밀도지단백증고56례。Logistic 회귀결과：류풍습관절염빈혈여혈청청단백강저상관，염증활동성지표홍세포침강솔、C-반응단백여혈청청단백、혈소판정부상관。결론：준의시류풍습관절염환병솔녀성교고，이농민위주，단무명현거주지역성차이。주원환자다위병변적급성기，다합병저단백혈증、빈혈급혈지대사이상。환자합병감염점20%，이폐부간질성병변위주。흡연가능시준의시남성 RA 환자발병적위험인소지일。
[ABSTRACT] Objective:To retrospectively analyze the clinical data of patients with rheumatoid arthritis in Zunyi City and find the clinical epidemiological characteristics to provide more clinical evidence for the diagnosis and treatment of rheumatoid arthritis.Methods:The clinical data of patients with rheumatoid arthritis in the First People’s Hospital of Zunyi City from December 2013 to February 2008 were retrospectively analyzed.General condition and laboratory index of patients were also statistically analyzed.Results:Among 320 patients with rheumatoid arthritis,68 were males and 252 were females.Occupational characteristics:106 cases were office workers,144 cases were farmers,34 cases were common workers,and 36 cases had no work.Living condition:146 cases lived in the city,156 lived in the countryside,and 18 cases lived in rural-urban fringe zone. 65 cases were concurrently infected,among which 48 cases had pulmonary infection and 17 cases had urinary tract infection.Smoking condition:52 cases had smoking history (44 males and 8 females).Laboratory results:288 cases with positive rheumatoid factor,255 cases with positive anti CCP antibody,258 cases with elevated C- reactive protein,125 cases with elevated erythrocyte sedimentation rate,158 cases with anemia,102 cases with decreased total protein,214 cases with lowered albumin,49 cases with increased triglyceride,101 cases with decreased high density lipoprotein,and 56 cases with increased low density lipoprotein.Logistic regression results:For rheumatoid arthritis,anemia was correlated with the decrease of serum albumin,and erythrocyte sedimentation rate and C-reactive protein were negatively related with serum albumin and platelets.Conclusion:The prevalence rate of rheumatoid arthritis among the female in Zunyi City is higher,the majority of which are farmers,but there is no obvious difference in residential area.A majority of hospitalized patients are mostly in the acute stage,mostly with hypoproteinemia,anemia and abnormal lipid metabolism.In Zunyi City,20% of patients with rheumatoid arthritis are concurrently infected with pulmonary interstitial lesions.Smoking may be one of the risk factors of male with rheumatoid arthritis.
