CAJ | 학술논문

目的：研究分析不同时机将犬牙移入牵张成骨区后龈沟液的天门冬氨酸氨基转移酶（AST ）水平变化。方法8只无牙周疾病且正常恒牙列beag le犬行牵张成骨术后分为两组（2周和6周），均行牙齿移入牵张成骨新骨区。观察对实验牙加力1、2、3、7、14、28 d后龈沟液中AST水平变化。结果两组实验牙龈沟液AST水平前3 d均存在上升趋势，且2周组上升较6周组明显；7 d后AST水平呈现下降趋势，在21 d达最低，并逐渐恢复；当28 d时AST水平再次上升。结论牵张成骨2周后实验牙移入新骨区龈沟液AST整体水平较6周后明显升高，但随着时间的推移AST水平改变并非呈线性升高。
목적：연구분석불동시궤장견아이입견장성골구후간구액적천문동안산안기전이매（AST ）수평변화。방법8지무아주질병차정상항아렬beag le견행견장성골술후분위량조（2주화6주），균행아치이입견장성골신골구。관찰대실험아가력1、2、3、7、14、28 d후간구액중AST수평변화。결과량조실험아간구액AST수평전3 d균존재상승추세，차2주조상승교6주조명현；7 d후AST수평정현하강추세，재21 d체최저，병축점회복；당28 d시AST수평재차상승。결론견장성골2주후실험아이입신골구간구액AST정체수평교6주후명현승고，단수착시간적추이AST수평개변병비정선성승고。
Objective To observe the dynamic changes of aspartate transaminase(AST ) in gingival crevicular fluid on tooth movement in new bone area after distraction osteogenesis at different time .Methods The distraction osteogenesis surgical proce‐dure was performed in 8 beagle dogs without periodontal disease and normal teeth ,experimental teeth were transplanted into the bone regeneration area after 2 weeks and after 6 weeks .Comparative analysis AST of each time (1 ,2 ,3 ,7 ,14 ,28 d after distraction) dynamic changes in gingival crevicular fluid .Results The AST level of gingival crevicular fluid in experimental tooth was rising for the first three days ,and the group of two weeks were significantly higher than 6 weeks ;AST levels after 7 d showed a trend of de‐cline ,down to the lowest point at 21 d ,and gradually restored ,AST levels reached a higher level again in the 28 d .Conclusion The AST level of experimental teeth increased significantly after 2 weeks than after 6 weeks ,but over time the AST level change is not linear ,this change has certain guiding significance for the clinical research in the future .