CAJ | 학술논문

目的：观察果酸换肤在痤疮治疗方面的疗效和安全性。方法选择64例痤疮患者，随机分为治疗组32例和对照组32例。治疗组为果酸治疗，每2周1次，共4次；对照组给予克林霉素甲硝唑搽剂外用，每日2次，连续8周。10周后2组进行疗效比较。结果治疗4次后治疗组和对照组有效率分别为84.4%、50.0%；痊愈率分别为43.8%、18.8%。2组之间痊愈率及有效率比较均有统计学意义（P＜0.05）。结论果酸换肤治疗轻中度痤疮高效、安全而方便，患者满意度高。
목적：관찰과산환부재좌창치료방면적료효화안전성。방법선택64례좌창환자，수궤분위치료조32례화대조조32례。치료조위과산치료，매2주1차，공4차；대조조급여극림매소갑초서차제외용，매일2차，련속8주。10주후2조진행료효비교。결과치료4차후치료조화대조조유효솔분별위84.4%、50.0%；전유솔분별위43.8%、18.8%。2조지간전유솔급유효솔비교균유통계학의의（P＜0.05）。결론과산환부치료경중도좌창고효、안전이방편，환자만의도고。
Objective To investigate the clinical efficacy and safety of alpha hydroxy acid in the treatment of acne.Methods 64 cases of acne patients were randomly divided into treatment group and control group with 32 cases in each group. The patients in the treatment group were treated with alpha hydroxy acid four times of, once every other week. While Topical clindamycin and metronidazole liniment were given to the patients in control group twice a day lasting for eight weeks. The results of the two groups were comparied after treating for 10 weeks.Results The effective ratio of treating group was 84.4%, while that of the control group was 50.0%. The cure ratio of treating group was 43.8%, while control droup was 18.8%. The cure ratio and effective ratio of the treatment group and the control group were satistically significant.Conclusion Alpha hydroxy acid is an effective, safety and convenient method for mild to moderate acne vulgaris, which has higher satisfaction.