CAJ | 학술논문

目的：探讨复荣通脉胶囊治疗糖尿病周围神经病变的临床疗效。方法选择2013年1月至2015年1月医院收治的糖尿病周围神经病变患者97例，将其随机分为观察组49例、对照组48例，对照组采取西医治疗方案，观察组在对照组基础上联合运用复荣通脉胶囊，2组均治疗3个月，比较2组患者临床疗效、治疗前后症状积分、TCSS评分、神经传导速度以及安全性。结果观察组治疗总有效率为83.67%，对照组治疗总有效率为64.58%，2组差异具有统计学意义（P<0.05）；2组患者治疗后临床症状积分、TCSS评分均较治疗前显著改善，且观察组改善情况显著优于对照组（P<0.05）；2组患者治疗前双侧腓总神经运动神经、感觉神经的传速度无统计学意义（P>0.05），治疗后2组患者神经传导速度均明显改善（P<0.05），且观察组改善情况显著优于对照组（P<0.05）。结论复荣通脉胶囊联合西医营养神经、改善微循环常规方案治疗糖尿病周围神经病变疗效显著，可显著改善患者临床症状以及神经病变，值得临床推广运用。
목적：탐토복영통맥효낭치료당뇨병주위신경병변적림상료효。방법선택2013년1월지2015년1월의원수치적당뇨병주위신경병변환자97례，장기수궤분위관찰조49례、대조조48례，대조조채취서의치료방안，관찰조재대조조기출상연합운용복영통맥효낭，2조균치료3개월，비교2조환자림상료효、치료전후증상적분、TCSS평분、신경전도속도이급안전성。결과관찰조치료총유효솔위83.67%，대조조치료총유효솔위64.58%，2조차이구유통계학의의（P<0.05）；2조환자치료후림상증상적분、TCSS평분균교치료전현저개선，차관찰조개선정황현저우우대조조（P<0.05）；2조환자치료전쌍측비총신경운동신경、감각신경적전속도무통계학의의（P>0.05），치료후2조환자신경전도속도균명현개선（P<0.05），차관찰조개선정황현저우우대조조（P<0.05）。결론복영통맥효낭연합서의영양신경、개선미순배상규방안치료당뇨병주위신경병변료효현저，가현저개선환자림상증상이급신경병변，치득림상추엄운용。
Objective To investigate the clinical efifcacy of Furongtongmai capsule in the treatment of diabetic peripheral neuropathy.Methods 97 cases of patients with diabetic peripheral neuropathy were diagnosed from January 2013 to January 2015, which were randomly divided into observation group(n=49)and control group(n=48). The control group were treated with western medicine treatment and the observation group were treated with Furongtongmai capsule on the basis of the treatment in the control group.Two sets of treatments were three months. A comparison of the clinical efficacy, symptom score before and after the treatment, TCSS score, nerve conduction velocity and Security in both groups were made.Results The total effective rate in the observation group was 83.67% and that in the control group ws 64.58%, there was a statistical signiifcance(P<0.05); after the treatments, the symptom score and TCSS score in both groups were signiifcantly better than that of the before treatment, and the symptom score and TCSS score in the observation group were signiifcantly superior to that of the control group(P<0.05). There was no difference in bilateral peroneal nerve motor nerve and sensory nerve of transmission speed before the treatment(P>0.05). The NCV in both groups were signiifcantly improved after the treatment(P>0.05), and the mend matters in the observation group were significantly superior to the control group(P<0.05).Conclusion The clinical efficacy of the Furongtongmai capsule combined with western medicine for nourishing the nerves and improving micro-circulation of conventional scheme is signiifcant, which can signiifcantly improve the clinical symptoms and neuropathy, it is worthy to be popularized and applied.