中国基层医药
中國基層醫藥
중국기층의약
Chinese Journal of Primary Medicine and Pharmacy
2015年
23期
3655-3658
,共4页
肺疾病,慢性阻塞性%肺功能%摄氧效率%运动耐力
肺疾病,慢性阻塞性%肺功能%攝氧效率%運動耐力
폐질병,만성조새성%폐공능%섭양효솔%운동내력
Pulmonary disease,chronic obstructive%Lung function%Oxygen uptake efficiency%Movement endurance
目的:探讨摄氧效率与 COPD 稳定期患者运动耐力的相关性。方法选择2013年1月至2014年12月 COPD 稳定期患者50例为研究对象,50例患者中,按照病情严重程度,Ⅰ~Ⅱ级28例,Ⅲ~Ⅳ级22例;选择2013年1月至2014年12月50例 COPD 急性期患者为疾病对照组;选择2013年1月至2014年12月健康人群50名为健康对照组。检测研究对象用力肺活量(FVC)、第一秒用力呼气容积(FEV1)、FEV1/FVC、峰值摄氧量(peak VO2)、峰值摄氧量占预计值(peak VO2%pred)、摄氧效率斜率(OUES)、摄氧效率平台(OUEP)、无氧阈时的摄氧效率(OUE@AT)等指标,并对摄氧效率及运动耐力进行相关性分析。结果COPD组 FVC、FEV1、FEV1/FVC 等指标数值均小于对照组,差异有统计学意义(均 P <0.05),且 COPD 急性期患者FVC(2.86±0.36)L、FEV1(1.25±0.36)L、FEV1/FVC(50.16±5.37)%等指标数值均小于 COPD 稳定期的(3.12±0.46)L,(1.51±0.38)L,(60.16±6.16)%,差异有统计学意义(F =5.62、6.52、7.18,均 P <0.05)。COPD 组 peak VO2、peak VO2%pred、OUES、OUEP、OUE@AT 等指标数值均小于对照组,差异有统计学意义(均 P <0.05),且 COPD 急性期患者 peak VO2(1072.35±271.21)mL/min、peak VO2%pred(62.79±6.31)、OUES(1.59±0.29)、OUEP(25.72±3.42)、OUE@AT(26.75±3.12)等指标数值均小于 COPD 稳定期的(1190.67±286.21)mL/min,(70.76±6.27),(1.89±0.31),(31.46±4.05),(31.62±3.16),差异有统计学意义(F =15.16、9.79、6.15、8.76、8.92,均 P <0.05)。随着 COPD 稳定期患者病情严重程度的加重,peak VO2、peak VO2%pred、OUES、OUEP、OUE@AT 呈逐渐下降趋势[(1089.62±221.68)mL/min 比(1236.75±235.37)mL/min,(67.28±5.03)比(75.81±5.39),(1.62±0.18)比(2.04±0.25),(30.67±6.47)比(34.17±4.40),(30.31±3.42)比(36.59±3.63),F =16.92、12.71、4.27、8.75、7.59,均 P <0.05]。COPD 稳定期患者OUES、OUEP、OUE@AT 等摄氧效率指标与运动耐力指标 peak VO2%pred 均呈正相关(r =0.451、0.462、0.429,P =0.019、0.012、0.26),与 peak VO2均呈正相关(r =0.446、0.452、0.417,P =0.023、0.011、0.29)。结论COPD 患者摄氧效率及运动耐力均较健康人群降低,COPD 患者摄氧效率及运动耐力与 COPD 病情及严重程度有关,而 COPD 患者运动耐力对摄氧效率亦存在一定程度的影响。
目的:探討攝氧效率與 COPD 穩定期患者運動耐力的相關性。方法選擇2013年1月至2014年12月 COPD 穩定期患者50例為研究對象,50例患者中,按照病情嚴重程度,Ⅰ~Ⅱ級28例,Ⅲ~Ⅳ級22例;選擇2013年1月至2014年12月50例 COPD 急性期患者為疾病對照組;選擇2013年1月至2014年12月健康人群50名為健康對照組。檢測研究對象用力肺活量(FVC)、第一秒用力呼氣容積(FEV1)、FEV1/FVC、峰值攝氧量(peak VO2)、峰值攝氧量佔預計值(peak VO2%pred)、攝氧效率斜率(OUES)、攝氧效率平檯(OUEP)、無氧閾時的攝氧效率(OUE@AT)等指標,併對攝氧效率及運動耐力進行相關性分析。結果COPD組 FVC、FEV1、FEV1/FVC 等指標數值均小于對照組,差異有統計學意義(均 P <0.05),且 COPD 急性期患者FVC(2.86±0.36)L、FEV1(1.25±0.36)L、FEV1/FVC(50.16±5.37)%等指標數值均小于 COPD 穩定期的(3.12±0.46)L,(1.51±0.38)L,(60.16±6.16)%,差異有統計學意義(F =5.62、6.52、7.18,均 P <0.05)。COPD 組 peak VO2、peak VO2%pred、OUES、OUEP、OUE@AT 等指標數值均小于對照組,差異有統計學意義(均 P <0.05),且 COPD 急性期患者 peak VO2(1072.35±271.21)mL/min、peak VO2%pred(62.79±6.31)、OUES(1.59±0.29)、OUEP(25.72±3.42)、OUE@AT(26.75±3.12)等指標數值均小于 COPD 穩定期的(1190.67±286.21)mL/min,(70.76±6.27),(1.89±0.31),(31.46±4.05),(31.62±3.16),差異有統計學意義(F =15.16、9.79、6.15、8.76、8.92,均 P <0.05)。隨著 COPD 穩定期患者病情嚴重程度的加重,peak VO2、peak VO2%pred、OUES、OUEP、OUE@AT 呈逐漸下降趨勢[(1089.62±221.68)mL/min 比(1236.75±235.37)mL/min,(67.28±5.03)比(75.81±5.39),(1.62±0.18)比(2.04±0.25),(30.67±6.47)比(34.17±4.40),(30.31±3.42)比(36.59±3.63),F =16.92、12.71、4.27、8.75、7.59,均 P <0.05]。COPD 穩定期患者OUES、OUEP、OUE@AT 等攝氧效率指標與運動耐力指標 peak VO2%pred 均呈正相關(r =0.451、0.462、0.429,P =0.019、0.012、0.26),與 peak VO2均呈正相關(r =0.446、0.452、0.417,P =0.023、0.011、0.29)。結論COPD 患者攝氧效率及運動耐力均較健康人群降低,COPD 患者攝氧效率及運動耐力與 COPD 病情及嚴重程度有關,而 COPD 患者運動耐力對攝氧效率亦存在一定程度的影響。
목적:탐토섭양효솔여 COPD 은정기환자운동내력적상관성。방법선택2013년1월지2014년12월 COPD 은정기환자50례위연구대상,50례환자중,안조병정엄중정도,Ⅰ~Ⅱ급28례,Ⅲ~Ⅳ급22례;선택2013년1월지2014년12월50례 COPD 급성기환자위질병대조조;선택2013년1월지2014년12월건강인군50명위건강대조조。검측연구대상용력폐활량(FVC)、제일초용력호기용적(FEV1)、FEV1/FVC、봉치섭양량(peak VO2)、봉치섭양량점예계치(peak VO2%pred)、섭양효솔사솔(OUES)、섭양효솔평태(OUEP)、무양역시적섭양효솔(OUE@AT)등지표,병대섭양효솔급운동내력진행상관성분석。결과COPD조 FVC、FEV1、FEV1/FVC 등지표수치균소우대조조,차이유통계학의의(균 P <0.05),차 COPD 급성기환자FVC(2.86±0.36)L、FEV1(1.25±0.36)L、FEV1/FVC(50.16±5.37)%등지표수치균소우 COPD 은정기적(3.12±0.46)L,(1.51±0.38)L,(60.16±6.16)%,차이유통계학의의(F =5.62、6.52、7.18,균 P <0.05)。COPD 조 peak VO2、peak VO2%pred、OUES、OUEP、OUE@AT 등지표수치균소우대조조,차이유통계학의의(균 P <0.05),차 COPD 급성기환자 peak VO2(1072.35±271.21)mL/min、peak VO2%pred(62.79±6.31)、OUES(1.59±0.29)、OUEP(25.72±3.42)、OUE@AT(26.75±3.12)등지표수치균소우 COPD 은정기적(1190.67±286.21)mL/min,(70.76±6.27),(1.89±0.31),(31.46±4.05),(31.62±3.16),차이유통계학의의(F =15.16、9.79、6.15、8.76、8.92,균 P <0.05)。수착 COPD 은정기환자병정엄중정도적가중,peak VO2、peak VO2%pred、OUES、OUEP、OUE@AT 정축점하강추세[(1089.62±221.68)mL/min 비(1236.75±235.37)mL/min,(67.28±5.03)비(75.81±5.39),(1.62±0.18)비(2.04±0.25),(30.67±6.47)비(34.17±4.40),(30.31±3.42)비(36.59±3.63),F =16.92、12.71、4.27、8.75、7.59,균 P <0.05]。COPD 은정기환자OUES、OUEP、OUE@AT 등섭양효솔지표여운동내력지표 peak VO2%pred 균정정상관(r =0.451、0.462、0.429,P =0.019、0.012、0.26),여 peak VO2균정정상관(r =0.446、0.452、0.417,P =0.023、0.011、0.29)。결론COPD 환자섭양효솔급운동내력균교건강인군강저,COPD 환자섭양효솔급운동내력여 COPD 병정급엄중정도유관,이 COPD 환자운동내력대섭양효솔역존재일정정도적영향。
Objective To study correlation between oxygen uptaking efficiency and exercise endurance of patients with stable chronic obstructive pulmonary disease (COPD).Methods From January 2013 to December 2014,50 patients with COPD plateau were selected as the research subjects,and according to the severity,28 cases of gradeⅠ -Ⅱ,22 cases of grade Ⅲ -Ⅳ.50 COPD patients with acute phase of disease were selected as disease control group.50 healthy people were selected as healthy control group.The forced vital capacity (FVC),forced expiratory volume in first second (FEV1 ),FEV1 /FVC,peak oxygen uptake (peak VO2 ),peak oxygen uptake of expected value (peak VO2% Mr Pred),oxygen uptake efficiency slope (OUES),oxygen uptake efficiency platform (OUEP),when the anaerobic threshold (OUE @ AT)such as index,and the oxygen uptake efficiency and movement endurance were detected and analyzed.Results FVC,FEV1 ,FEV1 /FVC index values of COPD group were less than those of the control group,the differences were statistically significant (all P <0.05),and COPD patients with acute phase of FVC(2.86 ±0.36)L,FEV1 (1.25 ±0.36)L,FEV1 /FVC(50.16 ±5.37)% index values were less than COPD stabilization [(3.12 ±0.46)L,(1.51 ±0.38)L,(60.16 ±6.16)%)],the differences were statistically significant (all P <0.05).The peak VO2 ,peak VO2% Mr Pred,OUES,OUEP,OUE @ AT index values of COPD group were less than those of the control group,the differences were statistically significant (all P <0.05),and COPD patients with acute phase of peak VO2 (1 072.35 ±271.21)mL/min,peak VO2%pred(62.79 ±6.31),OUES(1.59 ±0.29),OUEP (25.72 ±3.42),OUE@AT(26.75 ±3.12)index values were less than patients with COPD stabilization[(1190.67 ± 286.21)mL/min,(70.76 ±6.27),(1.89 ±0.31 ),(31.46 ±4.05 ),(31.62 ±3.16)],the differences were statistically significant (all P <0.05).As the stabilization of disease severity in patients with COPD was aggravated, peak,VO2 peak VO2% Mr Pred,OUES,OUEP,OUE @ AT declined (1 089.62 ±221.68)mL/min vs.(1236.75 ± 235.37)mL/min,(67.28 ±5.03)vs.(75.81 ±5.39),(1.62 ±0.18)vs.(2.04 ±0.25),(30.67 ±6.47)vs. (34.17 ±4.40),(30.31 ±3.42)vs.(36.59 ±3.63)(F =16.92,12.71,4.27,8.75,7.59,P <0.05).Patients with COPD stabilization OUES,OUEP,OUE @ AT peak oxygen uptake efficiency indexes and movement endurance targets were positively correlated with VO2% Mr Pred (r =0.451,0.462,0.451,P =0.019,0.012,0.26),there was a positive correlation with peak VO2 (r =0.446,0.452,0.446,P =0.023,0.011,0.29).Conclusion COPD patients oxygen uptake efficiency and movement endurance than healthy people,patients with COPD oxygen uptake efficiency and movement endurance is associated with illness and severity of COPD,and COPD patients exercise endurance on the oxygen uptake efficiency also has a certain degree of influence.