CAJ | 학술논문

目的：观察平原人员急进高海拔地区后血氧饱和度、心率的变化，为高原地区医学救援提供参考。方法受试者从平原地区（海拔400 m）出发，出发前测定血氧饱和度、心率，乘飞机到达海拔4300 m 地区时测定血氧饱和度、心率；之后乘车到达海拔3200 m 目的地后动态连续监测血氧饱和度、心率，分别在到达后第1～7天测定血氧饱和度、心率；受试者在海拔3200 m 地区适应1周后乘车复返海拔4300 m 地区，再次测定血氧饱和度、心率。结果进入海拔4300、3200 m 地区后血氧饱和度明显下降，与平原地区血氧饱和度差异有统计学意义（P＜0．05）。进入海拔3200 m 地区后第6、7天血氧饱和度与第1天比较，差异有统计学意义（P＜0．05）。受试者乘飞机到达海拔4300 m 地区和乘车复返海拔4300 m 地区的氧饱和度差异有统计学意义（P＜0．05），心率间差异无统计学意义（P＞0．05）。结论随着海拔的增高，动脉血氧饱和度随之下降，平原人员急进海拔3200 m 地区第6天能初步适应，在较低海拔地区短时间适应后再进入高海拔地区人体能更好地适应。
목적：관찰평원인원급진고해발지구후혈양포화도、심솔적변화，위고원지구의학구원제공삼고。방법수시자종평원지구（해발400 m）출발，출발전측정혈양포화도、심솔，승비궤도체해발4300 m 지구시측정혈양포화도、심솔；지후승차도체해발3200 m 목적지후동태련속감측혈양포화도、심솔，분별재도체후제1～7천측정혈양포화도、심솔；수시자재해발3200 m 지구괄응1주후승차복반해발4300 m 지구，재차측정혈양포화도、심솔。결과진입해발4300、3200 m 지구후혈양포화도명현하강，여평원지구혈양포화도차이유통계학의의（P＜0．05）。진입해발3200 m 지구후제6、7천혈양포화도여제1천비교，차이유통계학의의（P＜0．05）。수시자승비궤도체해발4300 m 지구화승차복반해발4300 m 지구적양포화도차이유통계학의의（P＜0．05），심솔간차이무통계학의의（P＞0．05）。결론수착해발적증고，동맥혈양포화도수지하강，평원인원급진해발3200 m 지구제6천능초보괄응，재교저해발지구단시간괄응후재진입고해발지구인체능경호지괄응。
Objective To investigate the changes of blood oxygen saturation and heart rate after urgently going to high‐alti‐tude area ,so as to provide a reference for medical rescue in high‐altitude area .Methods Subjects left from the plain area with an al‐titude of 400 m .Blood oxygen saturation and heart rate were measured before departure and after reaching 4 300 m altitude region . Then the subjects were taken to the destination with an altitude of 3 200 m ,at which they received a dynamic continuous monitoring of blood oxygen saturation /heart rate at the 1st day ,2nd day ,3rd day ,4th day ,5th day ,6th day ,7th day after arrival .After adapting to the environment in 3 200 m altitude area for 1 week ,subjects were taken to the 4 300 m altitude region ,at which they were re‐measured blood oxygen saturation and heart rate .Results After entering the areas of 4 300 m altitude and 3 200 m altitude ,the blood oxygen saturation was significantly decreased compared with that in plain area (P< 0 .05) .The blood oxygen saturation at the 6th and 7th day after entering 3 200 m altitude area was statistically different when compared with that at the 1st day(P< 0 .05) . The blood oxygen saturation had statistical difference between reaching at 4 300 m altitude area for the first time and re‐entering 4 300 m altitude area ,while the heart rate had no statistical difference (P> 0 .05) .Conclusion The arterial oxygen saturation was de‐creased with the increase of altitude ;the people living in plain areas can preliminarily adapt to the environment at 6th day after reaching 3 200 m altitude regions ;people can better adapt to the high‐altitude environment by shortly living in lower‐altitude areas before re‐entering high‐altitude areas .