CAJ | 학술논문

功能磁共振成像作为一种新兴的神经影像学成像技术，其重要性受到神经、认知和心理学等领域的广泛关注。本文针对功能磁共振成像数据预处理过程中的头动校正环节，较为全面地阐述了国际知名脑功能成像软件包SPM的配准原理，并在此基础上提出了一种改进的配准方法，通过由粗到细的处理有效地提高了配准的准确度。此外，将差值平方和与归一化互信息的比值作为配准测度的思想弥补了单用一种测度的局限性，增加了配准过程的鲁棒性和可靠性。研究结果显示该方法具有一定的实际意义和应用价值。
공능자공진성상작위일충신흥적신경영상학성상기술，기중요성수도신경、인지화심이학등영역적엄범관주。본문침대공능자공진성상수거예처리과정중적두동교정배절，교위전면지천술료국제지명뇌공능성상연건포SPM적배준원리，병재차기출상제출료일충개진적배준방법，통과유조도세적처리유효지제고료배준적준학도。차외，장차치평방화여귀일화호신식적비치작위배준측도적사상미보료단용일충측도적국한성，증가료배준과정적로봉성화가고성。연구결과현시해방법구유일정적실제의의화응용개치。
As a new neuroimaging method, functional magnetic resonance (fMRI) with its importance of data processing has been widely recognized by neurology and cognitive psychology. Focusing on the realignment section in fMRI image preprocessing, this paper comprehensively describes the registration principle of SPM, an internationally-known software package which is specially designed for cerebral function imaging. An improved registration method is presented which effectively increases the accuracy. In addition, choosing the ratio of SSD and NMI as the registration measure can compensate for the limitation of using single measurement, which improves the robustness and reliability of the registration process. Experimental results prove the feasibility of this method.