CAJ | 학술논문

目的：观察肾康宁方对早期糖尿病肾病（DN）患者脂代谢的影响。方法：120例患者随机分为两组各60例。两组均予以常规治疗，治疗组加服肾康宁方，对照组口服依那普利片，疗程为8周，观察两组患者治疗前后尿微量白蛋白排泄率（UAER）、血脂等变化。结果：治疗组总有效率优于对照组，差异有显著性意义（P<0.05）；治疗组治疗后UAER、总胆固醇（TC）、低密度脂蛋白（LDL-C）均明显下降，与对照组比较，差异有显著性意义（P<0.05）。结论：肾康宁方可有效降低早期DN患者的UAER，并能改善血脂水平，对防治DN、延缓其进程具有积极意义。
목적：관찰신강저방대조기당뇨병신병（DN）환자지대사적영향。방법：120례환자수궤분위량조각60례。량조균여이상규치료，치료조가복신강저방，대조조구복의나보리편，료정위8주，관찰량조환자치료전후뇨미량백단백배설솔（UAER）、혈지등변화。결과：치료조총유효솔우우대조조，차이유현저성의의（P<0.05）；치료조치료후UAER、총담고순（TC）、저밀도지단백（LDL-C）균명현하강，여대조조비교，차이유현저성의의（P<0.05）。결론：신강저방가유효강저조기DN환자적UAER，병능개선혈지수평，대방치DN、연완기진정구유적겁의의。
Objective:To investigate clinical effects of the Shenkangning decoction on lipid metabolism in patients with early diabetic nephropathy. Methods:120 patients were randomly divided into 2 groups, 60 cases for each. Both groups received the conventional treatment;the treatment group was treated with the Shenkangning decocton more;and the control group was treated with Enalapril tablets more. A course of treatment was 8 weeks. Urinary albumin excretion rate , blood lipids and other changes in two groups were compared. Results:The total efifciency in the treatment group was better;the difference was statistically signiifcant. After the treatment, UAER, total cholesterol and low-density lipoprotein in the treatment group were signiifcantly decreased. Compared with the control group, there were signiifcant differences (P<0.05). Conclusion:The Shenkangning decoction could reduce UAER in early DN patients, and improve their blood lipid levels;it played an important role in the prevention and treatment of DN.