中医临床研究
中醫臨床研究
중의림상연구
Clinical Journal of Chinese Medicine
2015年
31期
19-21
,共3页
不稳定型心绞痛%芪参胶囊%超敏C反应蛋白%同型半胱氨酸
不穩定型心絞痛%芪參膠囊%超敏C反應蛋白%同型半胱氨痠
불은정형심교통%기삼효낭%초민C반응단백%동형반광안산
Unstable angina%The Qishen capsules%High-sensitivity C-reactive protein%Homocysteine
目的：研究芪参胶囊对不稳定型心绞痛患者CRP、TNF-α及同型半胱氨酸干预效果。方法：将113例不稳定型心绞痛患者随机均分为联合组及对照组。两组患者均采用冠心病二级预防方案，联合组患者加用芪参胶囊。1个月为1个疗程，两组患者共治疗3个疗程后评价疗效及检测炎症因子水平。结果：联合组总有效率为91.23%，对照组患者总有效率为76.79%。联合组患者总有效率高于对照组（P<0.05）；治疗后两组患者较治疗前Hcy、TNF-α及Hs-CRP均有明显降低（P<0.01），联合组患者治疗后Hcy、TNF-α及Hs-CRP水平均明显低于对照组（P<0.01）。结论：芪参胶囊可有效减轻不稳定型心绞痛患者炎症反应及炎症损伤，降低同型半胱氨酸及CRP水平，改善不稳定型心绞痛发作情况。
目的：研究芪參膠囊對不穩定型心絞痛患者CRP、TNF-α及同型半胱氨痠榦預效果。方法：將113例不穩定型心絞痛患者隨機均分為聯閤組及對照組。兩組患者均採用冠心病二級預防方案，聯閤組患者加用芪參膠囊。1箇月為1箇療程，兩組患者共治療3箇療程後評價療效及檢測炎癥因子水平。結果：聯閤組總有效率為91.23%，對照組患者總有效率為76.79%。聯閤組患者總有效率高于對照組（P<0.05）；治療後兩組患者較治療前Hcy、TNF-α及Hs-CRP均有明顯降低（P<0.01），聯閤組患者治療後Hcy、TNF-α及Hs-CRP水平均明顯低于對照組（P<0.01）。結論：芪參膠囊可有效減輕不穩定型心絞痛患者炎癥反應及炎癥損傷，降低同型半胱氨痠及CRP水平，改善不穩定型心絞痛髮作情況。
목적：연구기삼효낭대불은정형심교통환자CRP、TNF-α급동형반광안산간예효과。방법：장113례불은정형심교통환자수궤균분위연합조급대조조。량조환자균채용관심병이급예방방안，연합조환자가용기삼효낭。1개월위1개료정，량조환자공치료3개료정후평개료효급검측염증인자수평。결과：연합조총유효솔위91.23%，대조조환자총유효솔위76.79%。연합조환자총유효솔고우대조조（P<0.05）；치료후량조환자교치료전Hcy、TNF-α급Hs-CRP균유명현강저（P<0.01），연합조환자치료후Hcy、TNF-α급Hs-CRP수평균명현저우대조조（P<0.01）。결론：기삼효낭가유효감경불은정형심교통환자염증반응급염증손상，강저동형반광안산급CRP수평，개선불은정형심교통발작정황。
Objective:To investigate intervention effects of the Qishen capsules on CRP, TNF-α and homocysteine in unstable angina patients. Methods: 113 cases of unstable angina were randomly divided into the combined group and the control group. Both groups were treated with the coronary heart disease secondary prevention programs;and the combined group was given the Qishen capsule more, 1 month as a course. In 3 courses, the efifcacy and levels of inlfammatory factors were evaluated. Results:The total efifciency in the combined group was 91.23%, higher than 76.79%in the control group (P<0.05). After the treatment, Hcy, TNF-αand Hs-CRP in both groups were decreased obviously;And the combined group was lower than the control group (P<0.01). Conclusion:The Qishen capsule on CRP, TNF-αand homocysteine of unstable angina patients shows a signiifcant effect.
