CAJ | 학술논문

目的：了解抗菌药物对某院临床分离肠球菌属细菌的体外抗菌活性。方法对2013年6月—2014年7月该院临床各科室送检标本分离的188株肠球菌属细菌进行细菌鉴定及药物敏感试验。结果188株肠球菌属细菌其中屎肠球菌119株、粪肠球菌60株、鸟肠球菌9株，主要分布在尿和血标本，分别占34．57％和19．15％。未检出对达托霉素及利奈唑胺耐药的肠球菌属细菌；屎肠球菌对万古霉素的耐药率为1．68％，对青霉素、氨苄西林、高浓度庆大霉素、红霉素、左氧氟沙星的耐药率均＞70％；除四环素外，粪肠球对其他抗菌药物的耐药率均低于屎肠球菌，粪肠球对青霉素、氨苄西林耐药率较低，分别为16．67％，13．33％。结论达托霉素对该院肠球菌属细菌具有良好的抗菌效果。
목적：료해항균약물대모원림상분리장구균속세균적체외항균활성。방법대2013년6월—2014년7월해원림상각과실송검표본분리적188주장구균속세균진행세균감정급약물민감시험。결과188주장구균속세균기중시장구균119주、분장구균60주、조장구균9주，주요분포재뇨화혈표본，분별점34．57％화19．15％。미검출대체탁매소급리내서알내약적장구균속세균；시장구균대만고매소적내약솔위1．68％，대청매소、안변서림、고농도경대매소、홍매소、좌양불사성적내약솔균＞70％；제사배소외，분장구대기타항균약물적내약솔균저우시장구균，분장구대청매소、안변서림내약솔교저，분별위16．67％，13．33％。결론체탁매소대해원장구균속세균구유량호적항균효과。
Objective To investigate in vitro activity of antimicrobial agents against Enterococcus spp . isolated from clinic specimens in a hospital.Methods 188 Enterococcus spp . isolates from specimens sent by clinic depart-ments in June 2013-July 2014 were identified and performed antimicrobial susceptibility testing.Results Of 188 En-terococcus spp . isolates,119 were Enterococcus faecium (E.faecium),60 were E.faecalis ,and 9 were E.avium, these strains were mainly isolated from urine (34.57%)and blood specimens (19.15% ).No daptomycin and linezolid-resistant strain was detected;resistant rates of E.faecium to vancomycin was 1 .68%,to penicillin, ampicillin,high concentration gentamycin,erythromycin,and levofloxacin were all > 70%;except tetracycline, resistant rates of E.faecalis to the other antimicrobial agents were all lower than E.faecium,resistant rates of E. faecalis to penicillin and ampicillin were 16.67% and 13.33% respectively.Conclusion Daptomycin has high activity against Enterococcus spp . in this hospital.