中国感染控制杂志
中國感染控製雜誌
중국감염공제잡지
Chinese Journal of Infection Control
2015年
11期
740-742
,共3页
痰%亚胺培南%鲍曼不动杆菌%抗药性,微生物%医院感染
痰%亞胺培南%鮑曼不動桿菌%抗藥性,微生物%醫院感染
담%아알배남%포만불동간균%항약성,미생물%의원감염
sputum%imipenem%Acinetobacter baumannii%drug resistance,microbial%healthcare-associated infection
目的:了解痰中耐亚胺培南鲍曼不动杆菌(IRAB)检出情况、耐药性及病区分布。方法回顾性分析2009年1月1日—2013年9月30日某院痰标本分离的鲍曼不动杆菌(AB),比较 IRAB 和非 IRAB 的病区分布、耐药性,以及 IRAB 检出率的变化趋势。结果痰中共检出 AB 711株,其中 IRAB 442株,非 IRAB 269株。AB 主要分布在重症监护病房(ICU,39.10%)和神经内科(25.18%);ICU 检出 IRAB 254株(占57.47%),多于非 IRAB (24株,占8.92%),差异有统计学意义(χ2=165.50,P <0.05);IRAB 的检出率:ICU (91.37%)高于非 ICU (43.42%),差异有统计学意义(χ2=257.29,P <0.05)。2009—2013年 IRAB 的检出率持续升高(分别为25.30%、36.36%、74.68%、65.56%和90.07%)。IRAB 对阿米卡星的耐药率较低(27.25%),非 IRAB 对阿米卡星和哌拉西林/他唑巴坦的耐药率较低(7.31%、8.24%);除复方磺胺甲口恶唑外,IRAB 对其他抗菌药物的耐药率均高于非IRAB,差异均有统计学意义(均 P <0.05)。结论痰中 IRAB 检出率和耐药率均较高,临床应做到早培养、早治疗、早隔离,减少医院多重耐药菌的产生。
目的:瞭解痰中耐亞胺培南鮑曼不動桿菌(IRAB)檢齣情況、耐藥性及病區分佈。方法迴顧性分析2009年1月1日—2013年9月30日某院痰標本分離的鮑曼不動桿菌(AB),比較 IRAB 和非 IRAB 的病區分佈、耐藥性,以及 IRAB 檢齣率的變化趨勢。結果痰中共檢齣 AB 711株,其中 IRAB 442株,非 IRAB 269株。AB 主要分佈在重癥鑑護病房(ICU,39.10%)和神經內科(25.18%);ICU 檢齣 IRAB 254株(佔57.47%),多于非 IRAB (24株,佔8.92%),差異有統計學意義(χ2=165.50,P <0.05);IRAB 的檢齣率:ICU (91.37%)高于非 ICU (43.42%),差異有統計學意義(χ2=257.29,P <0.05)。2009—2013年 IRAB 的檢齣率持續升高(分彆為25.30%、36.36%、74.68%、65.56%和90.07%)。IRAB 對阿米卡星的耐藥率較低(27.25%),非 IRAB 對阿米卡星和哌拉西林/他唑巴坦的耐藥率較低(7.31%、8.24%);除複方磺胺甲口噁唑外,IRAB 對其他抗菌藥物的耐藥率均高于非IRAB,差異均有統計學意義(均 P <0.05)。結論痰中 IRAB 檢齣率和耐藥率均較高,臨床應做到早培養、早治療、早隔離,減少醫院多重耐藥菌的產生。
목적:료해담중내아알배남포만불동간균(IRAB)검출정황、내약성급병구분포。방법회고성분석2009년1월1일—2013년9월30일모원담표본분리적포만불동간균(AB),비교 IRAB 화비 IRAB 적병구분포、내약성,이급 IRAB 검출솔적변화추세。결과담중공검출 AB 711주,기중 IRAB 442주,비 IRAB 269주。AB 주요분포재중증감호병방(ICU,39.10%)화신경내과(25.18%);ICU 검출 IRAB 254주(점57.47%),다우비 IRAB (24주,점8.92%),차이유통계학의의(χ2=165.50,P <0.05);IRAB 적검출솔:ICU (91.37%)고우비 ICU (43.42%),차이유통계학의의(χ2=257.29,P <0.05)。2009—2013년 IRAB 적검출솔지속승고(분별위25.30%、36.36%、74.68%、65.56%화90.07%)。IRAB 대아미잡성적내약솔교저(27.25%),비 IRAB 대아미잡성화고랍서림/타서파탄적내약솔교저(7.31%、8.24%);제복방광알갑구악서외,IRAB 대기타항균약물적내약솔균고우비IRAB,차이균유통계학의의(균 P <0.05)。결론담중 IRAB 검출솔화내약솔균교고,림상응주도조배양、조치료、조격리,감소의원다중내약균적산생。
Objective To realize detection,antimicrobial resistance,and ward distribution of imipenem-resistant Acinetobacter baumannii (IRAB )from sputum.Methods AB strains isolated from sputum specimens in a hospital between January 1 ,2009 and September 30,2013 were analyzed retrospectively.Ward distribution,antimicrobial resistance,and isolation rates between IRAB and non-IRAB strains were compared.Results 711 AB strains were isolated from sputum,442 of which were IRAB,269 were non-IRAB.AB were mainly distributed in intensive care unit(ICU,39.10%)and neurology department (25.18%);detection rate of IRAB was significantly higher than non-IRAB in ICU (57.47%[n=254]vs 8.92%[n=24],χ2 =165.50,P <0.05),detection rate of IRAB in ICU was significantly higher than non-ICU (91 .37% vs 43.42%,χ2 =257.29,P <0.05).Detection rates of IRAB in 2009-2013 increased continuously (25.30%,36.36%,74.68%,65.56%,and 90.07%,respectively).The resistant rate of IRAB to amikacin was low (27.25%),resistant rates of non-IRAB to amikacin and piperacillin/tazobactam were both low (7.31 % and 8.24% respectively);except compound sulfamethoxazole,resistant rates of IRAB to other antimicrobial agents were all significantly higher than non-IRAB strains (all P < 0.05 ).Conclusion The detection rate and drug resistant rate of IRAB from sputum are both high,early culture,early treatment,and early isolation should be carried out to reduce the emergence of multidrug-resistant organisms.