CAJ | 학술논문

乳糜泻是一种遗传易感个体因摄入含麸质蛋白的谷物(祼小麦、大麦和麦)及其制品而诱发的慢性自身免疫性肠病，影响着世界上约1%人口的健康，并呈增长趋势；在中国可能也存在乳糜泻“冰山”现象，发生率远比原先预计的高；然而目前，中国从事医疗卫生和食品工业的专业人员对乳糜泻的认识仍存在不足。本文着重介绍了国内外在乳糜泻的流行病学、发病机制、临床症状、诊断和治疗等方面的研究进展。全面了解乳糜泻的相关知识，提高对乳糜泻的意识，有助于推动中国对乳糜泻的预防和控制，促进无麸质食品的开发和研究。
유미사시일충유전역감개체인섭입함부질단백적곡물(관소맥、대맥화맥)급기제품이유발적만성자신면역성장병，영향착세계상약1%인구적건강，병정증장추세；재중국가능야존재유미사“빙산”현상，발생솔원비원선예계적고；연이목전，중국종사의료위생화식품공업적전업인원대유미사적인식잉존재불족。본문착중개소료국내외재유미사적류행병학、발병궤제、림상증상、진단화치료등방면적연구진전。전면료해유미사적상관지식，제고대유미사적의식，유조우추동중국대유미사적예방화공제，촉진무부질식품적개발화연구。
ABSTRACT:Celiac disease (CD) is a chronic autoimmune enteropathy elicited in genetically predisposed in-dividuals by exposure to containing gluten-containing grains (i.e., wheat, barley, and rye), which is affecting about 1% of the world’s population and the prevalence of CD is still increasing. In China, an unseen ‘‘celiac iceberg’’, with the prevalence of CD in adults being higher than previously suggested, cannot be excluded. However, it is still lacking that awareness of CD among Chinese health professionals and food industry profes-sionals. This review focused on the pathogenesis, clinical manifestations, diagnosis, and management of CD. We should raise the awareness of the health and societal impact of CD, develop prevention strategies to guar-antee the health and quality of life of Chinese individuals suffering from CD, and promote the development of gluten-free food in China.