CAJ | 학술논문

目的：了解140例患者中段尿培养检出细菌的分布及耐药情况。方法：对患者中段尿液阳性标本，采用半自动细菌鉴定分析仪及药敏分析仪进行鉴定和药敏分析。结果：（1）中段尿培养检出病原菌以革兰氏阴性菌为主，占58.6%。（2）革兰氏阴性菌中，大肠埃希菌对青霉素、头孢呋辛、头孢噻肟及左氧氟沙星的耐药率均较高；肺炎克雷伯菌对头孢噻肟的耐药率较高；铜绿假单胞菌对头孢呋辛、头孢噻肟和复方新诺明的耐药率均达到100.0%。（3）革兰氏阳性菌中，葡萄球菌属对青霉素和头孢噻肟的耐药率较高；肠球菌属对庆大霉素、阿米卡星和红霉素的耐药率均达到100.0%。结论：临床上应加强对中段尿检测，病原菌对抗菌药物存在多药耐药性，指导临床合理用药，降低耐药率。
목적：료해140례환자중단뇨배양검출세균적분포급내약정황。방법：대환자중단뇨액양성표본，채용반자동세균감정분석의급약민분석의진행감정화약민분석。결과：（1）중단뇨배양검출병원균이혁란씨음성균위주，점58.6%。（2）혁란씨음성균중，대장애희균대청매소、두포부신、두포새우급좌양불사성적내약솔균교고；폐염극뢰백균대두포새우적내약솔교고；동록가단포균대두포부신、두포새우화복방신낙명적내약솔균체도100.0%。（3）혁란씨양성균중，포도구균속대청매소화두포새우적내약솔교고；장구균속대경대매소、아미잡성화홍매소적내약솔균체도100.0%。결론：림상상응가강대중단뇨검측，병원균대항균약물존재다약내약성，지도림상합리용약，강저내약솔。
ObjectiveTo investigate the bacteria distribution and drug resistance in patients with medistream urine.Meth-ods 140 patients with medistream urine were identified and determined by Semi-automatic system and susceptibility analyzers. Results(1) Gram-negative bacteria occupied 58.6% in medistream urine. (2) The rate of drug resistance of Escherichia coli to penicillin, cefuroxime, cefotaxime and levofloxacin was higher, respectively. The rate of drug resistance of Klebsiella pneumo-niae to cefotaxime was higher. The rate of drug resistance of Pseudomonas aeruginosa to cefuroxime, cefotaxime and cotrimoxa-zole was 100%. (3) The rate of drug resistance of Staphylococcus to penicilin, and cefotaxime was higher, respectively. The rate of drug resistance of Enterococcus to gentamicin, amikacin and erythromycin was 100%, respectively.Conclusion Pathogenic bacteria are always multidrug-resistant, it is necessary to focus on the etiology examination and the rational use of antibiotics so as to reduce the drug resistance rate.