CAJ | 학술논문

目的：探究抗菌药物专项整治对手术切口预防用药的影响。方法选取2013年7—12月(抗菌药物专项整治前)和2014年1—10月(抗菌药物专项整治后)在该院进行过切口手术的共1327例患者进行研究，按抗菌药物专项整治实施前后将这批患者分为对照组(653例)和观察组(674例)。观察两组的抗菌药物使用情况以及平均费用。结果观察组的药物使用率4011%明显低于对照组64.29%(P=0.0007)；观察组药物的利用率89.23%明显高于对照组药物利用率44.78%(P<0.05)；观察组平均用药时间(3.06±2.17)h、平均用药费用(884.6±40.9)元明显低于对照组平均用药时间(7.29±4.86)h、平均费用(1276.2±72.1)元(P<0.05)；观察组组用药总金额与DDDs排序比对照组相应值更接近1.0(P=0.0002)，购药与用药人数更同步。结论抗菌药物专项整治能够有效地降低药物的使用率、提高利用率、用药总金额与DDDs排序比，减少用药时间以及患者的平均费用(用于抗菌药物的费用)，具有较高的临床价值。
목적：탐구항균약물전항정치대수술절구예방용약적영향。방법선취2013년7—12월(항균약물전항정치전)화2014년1—10월(항균약물전항정치후)재해원진행과절구수술적공1327례환자진행연구，안항균약물전항정치실시전후장저비환자분위대조조(653례)화관찰조(674례)。관찰량조적항균약물사용정황이급평균비용。결과관찰조적약물사용솔4011%명현저우대조조64.29%(P=0.0007)；관찰조약물적이용솔89.23%명현고우대조조약물이용솔44.78%(P<0.05)；관찰조평균용약시간(3.06±2.17)h、평균용약비용(884.6±40.9)원명현저우대조조평균용약시간(7.29±4.86)h、평균비용(1276.2±72.1)원(P<0.05)；관찰조조용약총금액여DDDs배서비대조조상응치경접근1.0(P=0.0002)，구약여용약인수경동보。결론항균약물전항정치능구유효지강저약물적사용솔、제고이용솔、용약총금액여DDDs배서비，감소용약시간이급환자적평균비용(용우항균약물적비용)，구유교고적림상개치。
Objective To explore the effect of special treatment of antimicrobial drugs on the prevention of the surgical in-cision.Methods 1327 patients with incision surgery were randomly selected in July - December 2013(before special rectifi-cation of antimicrobial drugs)and January - October 2014(after the special rectification of antimicrobial drugs)from our hos-pital emergency department.The patients were divided into control group (653 cases) and observation group (674 cases) ac-cording to the implementation of the special rectification of antimicrobial drugs.Observe the utilization rate of antibacterial drugs, the use of the two groups, and the total cost of patients.Results Drug use rate 40.11% of observation group was sig-nificantly lower than that 64.29% of the control group (P=0.0007);drug utilization 89.23% of observation group was signifi-cantly higher than the control group’s drug utilization rate 44.78%(P<0.05).In the observation group,the average duration of medication (3.06±2.17) h,average cost of treatment (884.6±4.09) Yuan significantly lower than the control group,the average duration of medication (7.29 ±4.86) h,the average cost (1276.2 ±72.1) yuan (P<0.05);observation group treatment group total amount and DDDs sort than the control group,the corresponding values close to 1.0 (P=0.0002), the number of drugs and drug more synchronous.Conclusion Special treatment of antimicrobial drugs can effectively reduce the use of drugs, the uti-lization ratio,the total amount of the drug and DDDs sort,reduce the time and the average cost of patients (for the cost of antibiotics),with a high clinical value.