湖南师范大学学报（医学版）
湖南師範大學學報（醫學版）
호남사범대학학보（의학판）
Journal of Hunan Normal University (Medical Science)
2015年
5期
56-58,59
,共4页
外科重症监护室%气管插管%肺部感染%药敏分析
外科重癥鑑護室%氣管插管%肺部感染%藥敏分析
외과중증감호실%기관삽관%폐부감염%약민분석
surgical intensive care unit%endotracheal intubation%pulmonary infection%sensitivity analysis
目的：探讨外科重症监护室气管插管患者肺部感染的细菌药敏情况。方法：选择2012年8月～2014年2月在我院外科重症监护室诊治的120例患者，对肺部感染发病情况与临床资料进行调查；分离肺部感染患者的病原菌并纳入六种药物的药敏分析。结果：120例患者发生肺部感染43例，发生率为35.8%，其中死亡4例。多元多因素条件logistic回归模型结果发现年龄、导尿、动静脉插管、联合使用抗生素是导致肺部感染的主要独立危险因素。43例患者分离出病原菌43株，其中革兰氏阴性菌28株，革兰氏阳性菌11株，真菌4株。革兰氏阴性菌对头孢呋辛、左氧氟沙星、头孢唑林的敏感率都比较低。结论：外科重症监护室气管插管患者的肺部感染发生率比较高，预后比较差，病原菌多为革兰氏阴性菌，要积极根据药敏情况合理选择抗生素。
目的：探討外科重癥鑑護室氣管插管患者肺部感染的細菌藥敏情況。方法：選擇2012年8月～2014年2月在我院外科重癥鑑護室診治的120例患者，對肺部感染髮病情況與臨床資料進行調查；分離肺部感染患者的病原菌併納入六種藥物的藥敏分析。結果：120例患者髮生肺部感染43例，髮生率為35.8%，其中死亡4例。多元多因素條件logistic迴歸模型結果髮現年齡、導尿、動靜脈插管、聯閤使用抗生素是導緻肺部感染的主要獨立危險因素。43例患者分離齣病原菌43株，其中革蘭氏陰性菌28株，革蘭氏暘性菌11株，真菌4株。革蘭氏陰性菌對頭孢呋辛、左氧氟沙星、頭孢唑林的敏感率都比較低。結論：外科重癥鑑護室氣管插管患者的肺部感染髮生率比較高，預後比較差，病原菌多為革蘭氏陰性菌，要積極根據藥敏情況閤理選擇抗生素。
목적：탐토외과중증감호실기관삽관환자폐부감염적세균약민정황。방법：선택2012년8월～2014년2월재아원외과중증감호실진치적120례환자，대폐부감염발병정황여림상자료진행조사；분리폐부감염환자적병원균병납입륙충약물적약민분석。결과：120례환자발생폐부감염43례，발생솔위35.8%，기중사망4례。다원다인소조건logistic회귀모형결과발현년령、도뇨、동정맥삽관、연합사용항생소시도치폐부감염적주요독립위험인소。43례환자분리출병원균43주，기중혁란씨음성균28주，혁란씨양성균11주，진균4주。혁란씨음성균대두포부신、좌양불사성、두포서림적민감솔도비교저。결론：외과중증감호실기관삽관환자적폐부감염발생솔비교고，예후비교차，병원균다위혁란씨음성균，요적겁근거약민정황합리선택항생소。
ObjectiveTo investigate the bacterial susceptibility effects of pulmonary infection in the surgical intensive care unit patients with endotracheal intubation.MethodsSelected 120 pulmonary infection in the surgical intensive care unit with endotracheal intubation from August 2012 to February 2014 in our hospital, the incidence of pulmonary infection and clini-cal data were to investigate; the pathogens were isolated in the pulmonary infection patients and were given the six kinds of drugs sensitivity analysis.ResultsThere were 43 cases of pulmonary infection, the rate was 35.8%, 4 cases were died. Multiple multivariate conditional logistic regression model showed that age, catheterization, vascular catheter, the joint use of antibiot-ics were the major independent risk factors of pulmonary infection and there were 43 cases were isolated pathogens included 28 cases were Gram-negative bacteria, 11 cases were Gram-positive bacteria, 4 cases were fungi. The Gram-negative bacteria to cefuroxime, levofloxacin, cefazolin sensitivity rates were relatively low.ConclusionThe pulmonary infection in the surgical in-tensive care unit with endotracheal intubation is relatively high, the prognosis is relatively poor and the mostly bacteria is Gram-negative bacteria, we should actively reasonable choice the rational antibiotics based on susceptibility circumstances.
