CAJ | 학술논문

目的：分析非瓣膜性房颤抗凝治疗中华法林的应用效果。方法选择2012年4月～2014年3月80例非瓣膜性房颤患者，根据随机原则分组。其中对照组患者采用阿司匹林抗血小板聚集，实验组患者采用华法林抗凝。随访1年以上，对比两组患者血栓栓塞并发症和出血不良反应的差异。结果经数据统计发现，实验组患者随访期间栓塞并发症发生率低于对照组，组间有统计学差异（P＜0.05）。两组出血不良反应发生率无统计学差异（P＞0.05）。结论在非瓣膜性房颤的抗凝治疗中应用华法林可有效预防血栓形成，同时不增加出血风险。
목적：분석비판막성방전항응치료중화법림적응용효과。방법선택2012년4월～2014년3월80례비판막성방전환자，근거수궤원칙분조。기중대조조환자채용아사필림항혈소판취집，실험조환자채용화법림항응。수방1년이상，대비량조환자혈전전새병발증화출혈불량반응적차이。결과경수거통계발현，실험조환자수방기간전새병발증발생솔저우대조조，조간유통계학차이（P＜0.05）。량조출혈불량반응발생솔무통계학차이（P＞0.05）。결론재비판막성방전적항응치료중응용화법림가유효예방혈전형성，동시불증가출혈풍험。
Objective To analyze the effect of therapy of warfarin on non valvular atrial fibrillation anticoagulation.Methods From April 2012 to March 2014, 80 patients with non valvular atrial ifbrillation were grouped according to the random principle. The control group was treated with aspirin anticoagulation, the experimental group were treated with warfarin. Over one year of follow-up, the differences in cerebral embolism complications and bleeding of the two groups were compared.Results The incidence of cerebral embolism in the experimental group was signiifcantly lower than that in the control group (P<0.05). The incidence of adverse reactions in the two groups was not statistically significant (P>0.05). Conclusion The application of the Chinese method in the treatment of non valvular atrial ifbrillation can effectively prevent thrombosis, and not increase the risk of bleeding.