CAJ | 학술논문

目的：探讨振幅整合脑电图（aEEG）在监测早产儿早期脑损伤中的应用价值。方法使用脑电图仪对51例胎龄为26～36周的脑损伤早产儿（脑损伤组）和49例健康足月新生儿（对照组）分别于生后72 h 内进行监测，每次连续监测不低于2 h 。对比分析脑损伤组与对照组 aEEG 背景连续性、睡眠觉醒周期（周期性）。结果aEEG 背景连续性、睡眠周期性脑损伤组均较对照组低，差异有统计学意义（P＜0．05）；且脑损伤组 aEEG 背景波的异常程度明显高于对照组，差异有统计学意义（P＜0．05）。结论 aEEG 在早产儿脑损伤早期诊断和脑发育成熟度判断有很高的实用价值，值得临床推广应用。
목적：탐토진폭정합뇌전도（aEEG）재감측조산인조기뇌손상중적응용개치。방법사용뇌전도의대51례태령위26～36주적뇌손상조산인（뇌손상조）화49례건강족월신생인（대조조）분별우생후72 h 내진행감측，매차련속감측불저우2 h 。대비분석뇌손상조여대조조 aEEG 배경련속성、수면각성주기（주기성）。결과aEEG 배경련속성、수면주기성뇌손상조균교대조조저，차이유통계학의의（P＜0．05）；차뇌손상조 aEEG 배경파적이상정도명현고우대조조，차이유통계학의의（P＜0．05）。결론 aEEG 재조산인뇌손상조기진단화뇌발육성숙도판단유흔고적실용개치，치득림상추엄응용。
Objective To study the application value of amplitude integrated electroencephalography (aEEG) for early prediction and assessment of cerebral damage in premature infants .Methods 51 premature infants with cer‐ebral damage whose gestational ages were 26 - 36 weeks (cerebral damage group) and 49 healthy full‐term newborns (control group) were enrolled in the study .The aEEG of two groups were monitored during the first 72 h after birth , and the time of each continuous monitoring was 2 h or longer .The background continuity and sleep‐wake cycle in the aEEG of cerebral damage group and control group were analyzed and compared .Results Compared with control group ,the infants of cerebral damage group had lower presence of aEEG background continuity and sleep‐wake cycle , with significant difference (P< 0 .05) .The abnormity of aEEG background wave of cerebral damage group was sig‐nificantly worse than that of control group (P< 0 .05) .Conclusion aEEG is useful for the early diagnosis of cerebral damage in premature infants and the prediction of their cerebral developmental maturity ,which is worthy to be pro‐moted and applied in clinical .