临床荟萃
臨床薈萃
림상회췌
Clinical Focus
2015年
12期
1344-1346
,共3页
痛风%体征与症状%诊断%治疗
痛風%體徵與癥狀%診斷%治療
통풍%체정여증상%진단%치료
gout%signs and symptoms%therapy%diagnosis
痛风已是危害人们健康的常见疾病，近些年在痛风的诊治方面取得了很大的进展，本文主要就痛风的治疗，包括急性痛风性关节炎，降尿酸治疗和急性痛风的预防性治疗等方面进行介绍。急性痛风发作时应给予积极抗炎镇痛治疗，病情严重者可给予联合治疗。急性发作期在给予抗炎治疗的同时可给予降尿酸治疗，不影响急性发作的缓解。除非布司他可有效降低血尿酸外，新型降尿酸药物 lesinurad 有望与非布司他或别嘌醇联合应用，达到更好的降尿酸效果。
痛風已是危害人們健康的常見疾病，近些年在痛風的診治方麵取得瞭很大的進展，本文主要就痛風的治療，包括急性痛風性關節炎，降尿痠治療和急性痛風的預防性治療等方麵進行介紹。急性痛風髮作時應給予積極抗炎鎮痛治療，病情嚴重者可給予聯閤治療。急性髮作期在給予抗炎治療的同時可給予降尿痠治療，不影響急性髮作的緩解。除非佈司他可有效降低血尿痠外，新型降尿痠藥物 lesinurad 有望與非佈司他或彆嘌醇聯閤應用，達到更好的降尿痠效果。
통풍이시위해인문건강적상견질병，근사년재통풍적진치방면취득료흔대적진전，본문주요취통풍적치료，포괄급성통풍성관절염，강뇨산치료화급성통풍적예방성치료등방면진행개소。급성통풍발작시응급여적겁항염진통치료，병정엄중자가급여연합치료。급성발작기재급여항염치료적동시가급여강뇨산치료，불영향급성발작적완해。제비포사타가유효강저혈뇨산외，신형강뇨산약물 lesinurad 유망여비포사타혹별표순연합응용，체도경호적강뇨산효과。
ABSTRACT:Gout has already become a common disease endangering people's health.In recent years,great progresses have been achieved in the treatment of gout.The review focuses on the advances in the treatment of gout, including acute gouty arthritis,uric acid lowering treatment,the prophylactic treatment of acute gout flares and so on. A positive anti-inflammatory treatment should be given to the patients with acute gouty arthritis,and severe cases may be given combination therapy.Studies have confirmed that the uric acid lowering treatment combined with anti-inflammatory drugs can be given to the patients with gout flare,which will not affect the remission of gout flares. Besides febuxostat,which can effectively lower blood uric acid,lesinurad,as a new uric acid lowering drug,can be expected to obtain better effect in lowering uric acid when combined with febuxostat or allopurinol.
