CAJ | 학술논문

目的：分析细胞毒性药物不合理医嘱的主要类型原因及应对策略。方法对我院2013年2月～2015年5月用药配置中心5000例患者的细胞毒性药物长期医嘱进行审核，并按照类型的不同对其进行划分。结果5000例细胞毒性药物长期医嘱中，不合理医嘱例数为34例，比例为0.68%。34例患者的不合理医嘱主要可分为药物用量及用法不当、溶媒选择不合理、溶媒量偏多、溶媒量偏少、其他等类型，百分比分别为11.76%、44.12%、20.59%、14.71%、8.82%。结论加强对细胞毒性药物不合理医嘱的类型、原因分析，同时提升药师对细胞毒性药物应用重视程度，并加强细胞毒性药物长期医嘱的审核处理，可有效减少不合理医嘱的发生，从而有效确保细胞毒性药物临床应用的安全性和有效性。
목적：분석세포독성약물불합리의촉적주요류형원인급응대책략。방법대아원2013년2월～2015년5월용약배치중심5000례환자적세포독성약물장기의촉진행심핵，병안조류형적불동대기진행화분。결과5000례세포독성약물장기의촉중，불합리의촉례수위34례，비례위0.68%。34례환자적불합리의촉주요가분위약물용량급용법불당、용매선택불합리、용매량편다、용매량편소、기타등류형，백분비분별위11.76%、44.12%、20.59%、14.71%、8.82%。결론가강대세포독성약물불합리의촉적류형、원인분석，동시제승약사대세포독성약물응용중시정도，병가강세포독성약물장기의촉적심핵처리，가유효감소불합리의촉적발생，종이유효학보세포독성약물림상응용적안전성화유효성。
Objective To analyze the cytotoxic drugs and irrational prescriptions of the main types of coping strategies.MethodsFrom February 2013 to May 2015, cytotoxic drug in drug distribution center configuration of 5 000 cases of patients with long-term prescription were analyzed, and in accordance with the different types of its division. Results5 000 of cytotoxic drugs in long-term medical advice, medical advice unreasonable number of cases 34 cases, the ratio was 0.68%. 34 patients of irrational prescriptions can be divided into the amount of drugs and improper usage, vehicle selection unreasonable, solvent volume side, solvent less than normal, the other other types, percentages were 11.76%, 44.12%, 20.59%, 14.71%, 8.82%.Conclusion Strengthening of cytotoxic drugs irrational prescriptions of type, cause analysis, while increasing emphasis on pharmacists application of cytotoxic drugs, while strengthening the review process of long-term prescription of cytotoxic drugs, can effectively reduce the incidence of irrational prescriptions, thereby, to ensure the safety and efifcacy of cytotoxic drugs in clinical applications.