CAJ | 학술논문

目的：探讨曲美他嗪联合美托洛尔对冠心病心力衰竭患者心功能的改善作用。方法选择我院2014年3月～2015年1月收治的冠心病心力衰竭患者102例为研究对象，以随机数字表法分组，观察组51例，对照组51例，两组患者均采取常规治疗方案，对照组加用美托洛尔治疗，观察组加美托洛尔联合曲美他嗪治疗，对两组患者治疗后心功能进行观察。结果治疗前两组患者心功能各项指标无明显差异，治疗后均有改善，观察组治疗后心功能指标优于对照组，差异存在统计学意义（P＜0.05）；对照组不良反应发生率9.80%，对照组为11.76%，两组差异无统计学意义（P＞0.05）。结论曲美他嗪联合美托洛尔对冠心病心力衰竭进行治疗具有较好疗效，两者可起到协同作用，促进心功能改善。
목적：탐토곡미타진연합미탁락이대관심병심력쇠갈환자심공능적개선작용。방법선택아원2014년3월～2015년1월수치적관심병심력쇠갈환자102례위연구대상，이수궤수자표법분조，관찰조51례，대조조51례，량조환자균채취상규치료방안，대조조가용미탁락이치료，관찰조가미탁락이연합곡미타진치료，대량조환자치료후심공능진행관찰。결과치료전량조환자심공능각항지표무명현차이，치료후균유개선，관찰조치료후심공능지표우우대조조，차이존재통계학의의（P＜0.05）；대조조불량반응발생솔9.80%，대조조위11.76%，량조차이무통계학의의（P＞0.05）。결론곡미타진연합미탁락이대관심병심력쇠갈진행치료구유교호료효，량자가기도협동작용，촉진심공능개선。
Objective To study the trimetazidine joint metoprolol the improvement of heart function in patients with coronary heart disease heart failure.Methods From March 2014 to January 2015, 102 patients with coronary heart disease, heart failure as the research object, by the method of random Numbers table group, 51 cases of observation group, control group in 51 cases, two groups of patients were treated with conventional scheme, the control group treated with metoprolol, observation group with metoprolol combined trimetazidine treatment, for the treatment of two groups of patients to look at the middle of the back function.Results No difference between the two groups of patients with cardiac function indicators before and after the treatment are improved, the middle of the back function index observation treatment group was better than control group, there are statistically signiifcant difference (P< 0.05). Control group 9.80% incidence of adverse reactions, the control group was 9.80%, the difference between the two groups has no statistical signiifcance (P> 0.05). Conclusion Trimetazidine combined metoprolol has good curative effect on coronary heart disease heart failure treatment, both can have synergy, improve heart function.