上海医药
上海醫藥
상해의약
Shanghai Medical & Pharmaceutical Journal
2015年
22期
39-42
,共4页
卢逸烨%余佩毅%宋锐%袁艳
盧逸燁%餘珮毅%宋銳%袁豔
로일엽%여패의%송예%원염
高尿酸血症%患病率%老年人
高尿痠血癥%患病率%老年人
고뇨산혈증%환병솔%노년인
hyperuricemia%prevalence rate%old people
目的：调查上海市打浦桥社区65岁以上体检人群的高尿酸血症患病率，早期发现无症状高尿酸血症患者，分析相关危险因素。方法：收集2013年上海市打浦桥社区1540例65岁以上体检人群，其中男680例，女860例，调查高尿酸血症患病率和男、女患病率的差异。同时，按尿酸水平将患者分为高尿酸血症组541例和对照组（无高尿酸血症组）999例，分析导致高尿酸血症的相关危险因素。结果：高尿酸血症患病率为35.13%（541/1540），其中男性为35.44%（241/680），女性为34.88%（300/860），差异无统计学意义（P＞0.05）。Logistic回归分析发现，高龄、高体质指数、高三酰甘油血症、高肌酐、高尿素氮等为高尿酸血症的危险因素，而血清高密度脂蛋白水平高为保护因素（P均＜0.01）。结论：高尿酸血症与多种代谢疾病相关，老年人高尿酸血症患病率较高。建议65岁以上人群定期测血尿酸水平，及时发现患者并早期干预。
目的：調查上海市打浦橋社區65歲以上體檢人群的高尿痠血癥患病率，早期髮現無癥狀高尿痠血癥患者，分析相關危險因素。方法：收集2013年上海市打浦橋社區1540例65歲以上體檢人群，其中男680例，女860例，調查高尿痠血癥患病率和男、女患病率的差異。同時，按尿痠水平將患者分為高尿痠血癥組541例和對照組（無高尿痠血癥組）999例，分析導緻高尿痠血癥的相關危險因素。結果：高尿痠血癥患病率為35.13%（541/1540），其中男性為35.44%（241/680），女性為34.88%（300/860），差異無統計學意義（P＞0.05）。Logistic迴歸分析髮現，高齡、高體質指數、高三酰甘油血癥、高肌酐、高尿素氮等為高尿痠血癥的危險因素，而血清高密度脂蛋白水平高為保護因素（P均＜0.01）。結論：高尿痠血癥與多種代謝疾病相關，老年人高尿痠血癥患病率較高。建議65歲以上人群定期測血尿痠水平，及時髮現患者併早期榦預。
목적：조사상해시타포교사구65세이상체검인군적고뇨산혈증환병솔，조기발현무증상고뇨산혈증환자，분석상관위험인소。방법：수집2013년상해시타포교사구1540례65세이상체검인군，기중남680례，녀860례，조사고뇨산혈증환병솔화남、녀환병솔적차이。동시，안뇨산수평장환자분위고뇨산혈증조541례화대조조（무고뇨산혈증조）999례，분석도치고뇨산혈증적상관위험인소。결과：고뇨산혈증환병솔위35.13%（541/1540），기중남성위35.44%（241/680），녀성위34.88%（300/860），차이무통계학의의（P＞0.05）。Logistic회귀분석발현，고령、고체질지수、고삼선감유혈증、고기항、고뇨소담등위고뇨산혈증적위험인소，이혈청고밀도지단백수평고위보호인소（P균＜0.01）。결론：고뇨산혈증여다충대사질병상관，노년인고뇨산혈증환병솔교고。건의65세이상인군정기측혈뇨산수평，급시발현환자병조기간예。
Objective:To investigate the incidence rate of hyperuricemia in the population over 65 years old who had the physical examination in Dapuqiao Community in Shanghai to early ifnd out the patients with asymptomatic hyperuricemia and analyze the related risk factors.Methods:In 2013, 1 540 cases over 65 years old were collected in Dapuqiao Community in Shanghai, among them 680 were the male and 860 the female. The prevalence of hyperuricemia and the differences between the male and female were investigated. At the same time, the patients were divided into a hyperuricemia group with 541 cases and a control group (no hyperuricemia group) with 999 cases according to the level of uric acid and the relative risk factors which caused hyperuricemia were analyzed.Results:The incidence rate of hyperuricemia was 35.13% (541/1 540), and among them, the male accounted for 35.44% (241/680), and the female 34.88% (300/860), and the differences had no statistical signiifcance (P>0.05). The logistic regression analysis found that the old age, high BMI, hypertriglyceridemia, high creatinine, high blood urea nitrogen, and others were the risk factors of hyperuricemiabut thehigh HDL cholesterol level was the protective factor (P<0.01). Conclusion: Hyperuricemia is associated with a variety of metabolic diseases and the elderly people have the high prevalence of hyperuricemia. It is suggested that the regular blood uric acid level be tested for the elderly people over 65 years old to ifnd out the patients and intervene them early.
