CAJ | 학술논문

目的：观察脉冲射频联合神经阻滞治疗眼睑带状疱疹神经痛的疗效分析。 　　方法：2011－01／2014－08张家港市第一人民医院诊治的81例81眼眼睑带状疱疹患者，随机分为A、B、C三组。 A组27例，全身静滴阿昔洛韦、地塞米松药物治疗。 B组27例，在阿昔洛韦抗病毒药物治疗基础上，复方倍他米松等眶上神经阻滞。 C组27例，在阿昔洛韦抗病毒药物治疗基础上，予脉冲射频联合神经阻滞治疗。比较三组治疗前，治疗后1、7、30、90d的疼痛视觉模拟评分（ visual analogue scale，VAS）、临床治疗效果、并发症等情况。 　　结果：A组患者治疗前，治疗后1、7、30、90 d VAS分别为8．2±1．5、7．3±1．6、6．5±1．4、6．1±1．1、5．9±0．7；B组患者治疗前，治疗后1、7、30、90d VAS分别为8．2±1．3、6．3±1．1、5．7±0．9、5．1±1．1、4．1±0．7；C组患者治疗前，治疗后1、7、30、90d VAS分别为8．1±1．5、2．1±0．7、2．2±0.8、2．9±0．7、2．7±0．8。 C组患者在脉冲射频联合神经阻滞治疗后疼痛明显缓解，在1、3 mo后疼痛评分虽略有恢复，但仍明显低于对照组。三组治疗后第1、7、30、90d VAS评分差异有统计学意义（ F＝10．320、5．207、2．364、2．805，均P＜0．05）。 C组患者除减轻疼痛外，无严重并发症，例如角膜知觉减退等，并且角膜炎及角膜溃疡发生的可能减少。 　　结论：脉冲射频联合神经阻滞治疗能迅速减轻疼痛，并减少该疾病引起的并发症，是眼睑带状疱疹神经痛的一种安全、有效的治疗方法。
목적：관찰맥충사빈연합신경조체치료안검대상포진신경통적료효분석。 　　방법：2011－01／2014－08장가항시제일인민의원진치적81례81안안검대상포진환자，수궤분위A、B、C삼조。 A조27례，전신정적아석락위、지새미송약물치료。 B조27례，재아석락위항병독약물치료기출상，복방배타미송등광상신경조체。 C조27례，재아석락위항병독약물치료기출상，여맥충사빈연합신경조체치료。비교삼조치료전，치료후1、7、30、90d적동통시각모의평분（ visual analogue scale，VAS）、림상치료효과、병발증등정황。 　　결과：A조환자치료전，치료후1、7、30、90 d VAS분별위8．2±1．5、7．3±1．6、6．5±1．4、6．1±1．1、5．9±0．7；B조환자치료전，치료후1、7、30、90d VAS분별위8．2±1．3、6．3±1．1、5．7±0．9、5．1±1．1、4．1±0．7；C조환자치료전，치료후1、7、30、90d VAS분별위8．1±1．5、2．1±0．7、2．2±0.8、2．9±0．7、2．7±0．8。 C조환자재맥충사빈연합신경조체치료후동통명현완해，재1、3 mo후동통평분수략유회복，단잉명현저우대조조。삼조치료후제1、7、30、90d VAS평분차이유통계학의의（ F＝10．320、5．207、2．364、2．805，균P＜0．05）。 C조환자제감경동통외，무엄중병발증，례여각막지각감퇴등，병차각막염급각막궤양발생적가능감소。 　　결론：맥충사빈연합신경조체치료능신속감경동통，병감소해질병인기적병발증，시안검대상포진신경통적일충안전、유효적치료방법。
? AIM: To analyze the curative effect of pulsed radiofrequency combined with nerve block in the treatment of eyelid postherpetic neuralgia( PHN) . ?METHODS:Eighty-one patients ( 81 eyes ) with eyelid herpes zoster from January 2011 to August 2014 in our hospital were randomly divided into three groups ( 27 patients in group A, 27 patients in group B and 27patients in group C ) . Patients in group A were treated with intravenous infusion of acyclovir and dexamethasone. Patients in group B were treated with intravenous infusion of acyclovir and supraorbital nerve block using compound betamethasonePatients in group C were treated with pulsed radiofrequency and nerve block along with the same medicine acyclovir.Visual analogue scale ( VAS ) before treatment and 1, 7, 30, 90d after treatments, clinical efficacy and complications during the treatments in the three groups were recorded and analyzed. ?RESULTS:The VAS of patients in group A before treatments and 1,7,30,90d after treatments were 8.2 ± 1.5,7.3±1.6,6.5±1.4,6.1±1.1,5.9±0.7repectively;those of group B were 8.2±1.3,6.3±1.1,5.7±0.9,5.1±1.1,4.1± 0.7;those of group C were 8.1±1.5,2.1±0.7,2.2±0.8,2.9 ±0.7, 2.7 ±0.8.Pain of patients in group C relieved quickly after treatments of pulsed radiofrequency combined with nerve block.After 1 and 3mo, the VAS of group C rose a little, but still significantly lower than that of the other groups.At 1, 7, 30 and 90d after treatments, differences on VAS of three groups were statistically significant ( F =10.320, 5.207, 2.364, 2.805;P<0.05 ). Patients in group C had no severe complications, such as corneal hypoesthesia etc.in addition to relieved pain. The occurrence of keratitis and keratohelcosis in group C were reduced. ?CONCLUSION:Pulsed radiofrequency combined with nerve block can rapidly relieve the pain of PHN, reduce the complications, and may be a safety and effective method for eyelid postherpetic neuralgia.