CAJ | 학술논문

自噬（ autophagy）是真核细胞中细胞器以及蛋白质等物质降解的主要过程，在维持体内平衡的过程中起到重要作用。人眼晶状体是一个由上皮细胞以及其分化而来的纤维细胞共同组成的无血管透明器官，晶状体细胞主要通过自噬途径来降解细胞器以及异常聚集的蛋白质以维持晶状体的透明。自噬功能的异常与白内障的发生发展密切相关。本文就自噬相关内容进行介绍，并概括总结了近年来细胞自噬在白内障形成过程中的研究进展。
자서（ autophagy）시진핵세포중세포기이급단백질등물질강해적주요과정，재유지체내평형적과정중기도중요작용。인안정상체시일개유상피세포이급기분화이래적섬유세포공동조성적무혈관투명기관，정상체세포주요통과자서도경래강해세포기이급이상취집적단백질이유지정상체적투명。자서공능적이상여백내장적발생발전밀절상관。본문취자서상관내용진행개소，병개괄총결료근년래세포자서재백내장형성과정중적연구진전。
? Autophagy, the main degradation process of organelles, protein and other substances in the eukaryotic cells, plays an important role in the maintenance of homeostasis.Lens is a transparent tissue without vessel, which is mainly composed of a layer of epithelium cells and differentiating fiber cells. To maintain the transparency of lens, lenticular cells degrade their organelles and abnormal aggregated protein through autophagy. Abnormal function of autophagy is closely related to the formation of cataract.This article is aimed to introduce the related knowledge of autophagy and summarize the research progress of autuphagy in the procedure of cataract formation.